Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

Influenza A virus (IAV) is the sole cause of the unpredictable influenza pandemics and
deadly zoonotic outbreaks and constitutes at least half of the cause of regular annual …

Metabolic engineering of microorganisms to produce desirable products on an industrial
scale can result in unbalanced cellular metabolic networks that reduce productivity and …

Sustainable or green chemistry has established firm ground providing essential design
criteria for the development of efficient chemical syntheses of complex, high added value …

Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis …

Flu is a serious health, medical, and economic problem, but no therapy is yet available that
has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after …

Over the last few decades, computer-aided drug design has emerged as a powerful
technique playing a crucial role in the development of new drug molecules. Structure-based …

Viral infections are initiated by attachment of the virus to host cell surface receptors,
including sialic acid-containing glycans. It is now possible to rapidly identify specific glycan …

Since the discovery of organic azides by Peter Grieß more than 140 years ago, numerous
syntheses of these energy‐rich molecules have been developed. In more recent times in …