Abstract γδ T cells constitute a sizeable and non-redundant fraction of the total T cell pool in
all jawed vertebrates, but in contrast to conventional αβ T cells they are not restricted by …

Ruminant γδ T cells were discovered in the mid-1980′ s shortly after a novel T cell receptor
(TCR) gene from murine cells was described in 1984 and the murine TCRγ gene locus in …

Many genomic analyses start by aligning sequencing reads to a linear reference genome.
However, linear reference genomes are imperfect, lacking millions of bases of unknown …

Abstract Workshop cluster 1 (WC1) molecules are part of the scavenger receptor cysteine-
rich (SRCR) superfamily and act as hybrid co-receptors for the γδ T cell receptor and as …

Human respiratory syncytial virus (HRSV) is a leading cause of severe lower respiratory tract
infection in children under five years of age. IL-17 and Th17 responses are increased in …

Goats and cattle diverged 30 million years ago but retain similarities in immune system
genes. Here, the caprine T cell receptor (TCR) gene loci and transcription of its genes were …

Mycobacterium bovis has the largest host range of the Mycobacterium tuberculosis complex
and infects domestic animal species, wildlife, and humans. The presence of global wildlife …

ABSTRACT T helper 17 (Th17)-associated cytokines are integral to the immune responses
to tuberculosis, initiating both protective and harmful inflammatory responses. The aim of the …

There are several instances of co-investigation and related discoveries and achievements in
bovine and human immunology; perhaps most interesting is the development of the BCG …

Gene transcription studies have identified dual roles for the cytokines IL-17A and IL-22 in
bovine tuberculosis, where they show potential as both predictors of vaccine success and …