[HTML][HTML] Interactions between modified fullerenes and proteins in cancer nanotechnology

M Serda, J Korzuch, D Dreszer… - Drug Discovery …, 2023 - Elsevier
Fullerenes have numerous properties that fill the gap between small molecules and
nanomaterials. Several types of chemical reaction allow their surface to be ornamented with …

[HTML][HTML] Carbon-based nanomaterials against SARS-CoV-2: Therapeutic and diagnostic applications

S Ahmadi, ME Warkiani, M Rabiee, S Iravani, N Rabiee - OpenNano, 2023 - Elsevier
COVID-19, which was first spread in China in 2019 and consequently spread worldwide, is
caused by the SARS-CoV-2. Today, various carbon-based nanomaterials such as …

Functionalized Fullerene for Inhibition of SARS‐CoV‐2 Variants

TM Page, C Nie, L Neander, TL Povolotsky, AK Sahoo… - small, 2023 - Wiley Online Library
As virus outbreaks continue to pose a challenge, a nonspecific viral inhibitor can provide
significant benefits, especially against respiratory viruses. Polyglycerol sulfates recently …

Fullerenes: historical background, novel biological activities versus possible health risks

C Pesado-Gómez, JS Serrano-García… - Coordination Chemistry …, 2024 - Elsevier
C 60 fullerene is an allotropic molecule made up of sixty carbon atoms, which adopts a
quasi-spherical geometry with twenty hexagonal faces and twelve pentagonal faces. This …

Fullerene derivatives for drug delivery against COVID-19: a molecular dynamics investigation of dendro [60] fullerene as nanocarrier of Molnupiravir

GI Giannopoulos - Nanomaterials, 2022 - mdpi.com
In this paper, a theoretical investigation is made regarding the possibility of using a water-
soluble derivative of C60 as a drug delivery agent for treating Coronavirus disease 2019 …

Enhanced Uptake and Phototoxicity of C60@albumin Hybrids by Folate Bioconjugation

A Cantelli, M Malferrari, EJ Mattioli, A Marconi, G Mirra… - Nanomaterials, 2022 - mdpi.com
Fullerenes are considered excellent photosensitizers, being highly suitable for
photodynamic therapy (PDT). A lack of water solubility and low biocompatibility are, in many …

Novel C60 Fullerenol-Gentamicin Conjugate–Physicochemical Characterization and Evaluation of Antibacterial and Cytotoxic Properties

A Nurzynska, P Piotrowski, K Klimek, J Król, A Kaim… - Molecules, 2022 - mdpi.com
This study aimed to develop, characterize, and evaluate antibacterial and cytotoxic
properties of novel fullerene derivative composed of C60 fullerenol and standard …

The emergence of carbon nanomaterials as effective nano-avenues to fight against COVID-19

J Sengupta, CM Hussain - Materials, 2023 - mdpi.com
COVID-19 (Coronavirus Disease 2019), a viral respiratory ailment that was first identified in
Wuhan, China, in 2019, and then expanded globally, was caused by Severe Acute …

Exploiting blood transport proteins as carborane supramolecular vehicles for boron neutron capture therapy

TD Marforio, EJ Mattioli, F Zerbetto, M Calvaresi - Nanomaterials, 2023 - mdpi.com
Carboranes are promising agents for applications in boron neutron capture therapy (BNCT),
but their hydrophobicity prevents their use in physiological environments. Here, by using …

Development of Masitinib Derivatives with Enhanced Mpro Ligand Efficiency and Reduced Cytotoxicity

CA Menendez, A Mohamed, GR Perez-Lemus… - Molecules, 2023 - mdpi.com
Recently, a high-throughput screen of 1900 clinically used drugs identified masitinib, an
orally bioavailable tyrosine kinase inhibitor, as a potential treatment for COVID-19. Masitinib …