A comprehensive review of emerging trends and innovative therapies in epilepsy management

S Ghosh, JK Sinha, S Ghosh, H Sharma, R Bhaskar… - Brain Sciences, 2023 - mdpi.com
Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial
number of patients facing drug-resistant epilepsy. This comprehensive review explores …

Translational approaches to the neurobiological study of conditional discrimination and inhibition: Implications for psychiatric disease.

S Sangha, JM Fitzgerald - Behavioral neuroscience, 2024 - psycnet.apa.org
There is a growing number of studies investigating discriminatory fear conditioning and
conditioned inhibition of fear to assess safety learning, in addition to extinction of cued fear …

Prefrontal multistimulus integration within a dedicated disambiguation circuit guides interleaving contingency judgment learning

JD Pastore, J Mayer, J Steinhauser, K Shuler… - Cell Reports, 2024 - cell.com
Understanding how cortical network dynamics support learning is a challenge. This study
investigates the role of local neural mechanisms in the prefrontal cortex during contingency …

A potential target for noninvasive neuromodulation of PTSD symptoms derived from focal brain lesions in veterans

SH Siddiqi, NS Philip, ST Palm, DM Carreon… - Nature …, 2024 - nature.com
Neuromodulation trials for the treatment of posttraumatic stress disorder (PTSD) have
yielded mixed results, and the optimal neuroanatomical target remains unclear. Here we …

Fear, defense, and emotion: A neuroethological understanding of the negative valence research domain criteria.

MS Fanselow, AN Hoffman - American Psychologist, 2024 - psycnet.apa.org
We describe the close correspondence between predatory imminence continuum theory
(PICT) and the National Institute of Mental Health's Research Domain Criteria (RDoC) for …

Brain–computer interfaces for neuropsychiatric disorders

LL Oganesian, MM Shanechi - Nature Reviews Bioengineering, 2024 - nature.com
Neuropsychiatric disorders such as major depression are a leading cause of disability
worldwide with standard treatments, including psychotherapy or medication, failing many …

Discovering how the amygdala shapes human behavior: From lesion studies to neuromodulation

CS Inman, MK Hollearn, L Augustin, JM Campbell… - Neuron, 2023 - cell.com
Case studies of patients with amygdala damage or those receiving direct amygdala
stimulation have informed our understanding of the amygdala's role in emotion and …

[HTML][HTML] Deep brain stimulation of the amygdala for treatment-resistant combat post-traumatic stress disorder: Long-term results

RJ Koek, J Avecillas-Chasin, SE Krahl… - Journal of Psychiatric …, 2024 - Elsevier
Deep brain stimulation (DBS) holds promise for neuropsychiatric conditions where
imbalance in network activity contributes to symptoms. Treatment-resistant Combat post …

Revisiting the role of computational neuroimaging in the era of integrative neuroscience

AM Loosen, A Kato, X Gu - Neuropsychopharmacology, 2024 - nature.com
Computational models have become integral to human neuroimaging research, providing
both mechanistic insights and predictive tools for human cognition and behavior. However …

Anatomical organization of the amygdala: A brief visual review

A Dalla Corte, G Pinzetta, AG Ruwel… - Cognitive and …, 2024 - journals.lww.com
The amygdala consists of a collection of nuclei that are deep within the medial temporal
lobe. Despite its small size, the amygdala is one of the most densely connected structures in …