Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application

K Zha, X Li, Z Yang, G Tian, Z Sun, X Sui… - NPJ Regenerative …, 2021 - nature.com
Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …

The potential role of synovial cells in the progression and treatment of osteoarthritis

Z Zou, H Li, K Yu, K Ma, Q Wang, J Tang, G Liu… - …, 2023 - Wiley Online Library
Osteoarthritis (OA), the commonest arthritis, is characterized by the progressive destruction
of cartilage, leading to disability. The Current early clinical treatment strategy for OA often …

Soft substrates direct stem cell differentiation into the chondrogenic lineage without the use of growth factors

T Roncada, R Bonithon, G Blunn… - Journal of Tissue …, 2022 - journals.sagepub.com
Mesenchymal stem cells (MSCs) hold great promise for the treatment of cartilage related
injuries. However, selectively promoting stem cell differentiation in vivo is still challenging …

Recent progress on the role of miR-140 in cartilage matrix remodelling and its implications for osteoarthritis treatment

L Duan, Y Liang, X Xu, Y Xiao, D Wang - Arthritis Research & Therapy, 2020 - Springer
Cartilage matrix remodelling homeostasis is a crucial factor in maintaining cartilage integrity.
Loss of cartilage integrity is a typical characteristic of osteoarthritis (OA). Strategies aimed at …

Regenerative medicine for equine musculoskeletal diseases

I Ribitsch, GL Oreff, F Jenner - Animals, 2021 - mdpi.com
Simple Summary Lameness due to musculoskeletal disease is the most common diagnosis
in equine veterinary practice. Many of these orthopaedic disorders are chronic problems, for …

Sources and therapeutic strategies of mesenchymal stem cells in regenerative medicine

M Kamal, D Kassem, KH Haider - Handbook of stem cell therapy, 2022 - Springer
During the past decade, mesenchymal stem cells (MSCs) have made their mark as a
potential weapon in regenerative medicine. Since their first isolation by Friedenstein in the …

Effect of polystyrene nanoplastics and their degraded forms on stem cell fate

GB Im, YG Kim, IS Jo, TY Yoo, SW Kim, HS Park… - Journal of Hazardous …, 2022 - Elsevier
Several studies have examined the effects of micro-and nanoplastics on microbes, cells, and
the environment. However, only a few studies have examined their effects—especially …

[HTML][HTML] Accentuating the sources of mesenchymal stem cells as cellular therapy for osteoarthritis knees—a panoramic review

S Muthu, M Jeyaraman, R Jain, A Gulati… - Stem Cell …, 2021 - ncbi.nlm.nih.gov
The large economic burden on the global health care systems is due to the increasing
number of symptomatic osteoarthritis (OA) knee patients whereby accounting for greater …

Allogenic synovia-derived mesenchymal stem cells for treatment of equine tendinopathies and desmopathies—Proof of concept

I Leal Reis, B Lopes, P Sousa, AC Sousa… - Animals, 2023 - mdpi.com
Simple Summary Horses are high-level athletic athletes prone to musculoskeletal injuries.
Tendon/ligament injuries are the most frequent types of injuries which that are very difficult to …

Osteochondral regeneration of the femoral medial condyle by using a scaffold-free 3D construct of synovial membrane-derived mesenchymal stem cells in horses

D Murata, S Ishikawa, T Sunaga, Y Saito… - BMC veterinary …, 2022 - Springer
Background Medical interventions for subchondral bone cysts in horses have been
extensively studied. This study investigated the regeneration of articular cartilage and …