[HTML][HTML] Role of m6A RNA methylation in cardiovascular disease
Y Qin, L Li, E Luo, J Hou, G Yan… - International …, 2020 - spandidos-publications.com
Abstract N6‑methyladenosine (m6A) is the most prevalent and abundant type of internal post‑
transcriptional RNA modification in eukaryotic cells. Multiple types of RNA, including …
transcriptional RNA modification in eukaryotic cells. Multiple types of RNA, including …
The role of N6-methyladenosine mRNA in the tumor microenvironment
M Li, X Zha, S Wang - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
In recent years, the most widely distributed eukaryotic messenger RNA (mRNA)
modification, N6-methyladenosine (m6A), has received a large amount of interest, in part …
modification, N6-methyladenosine (m6A), has received a large amount of interest, in part …
[HTML][HTML] Hypoxia inducible lncRNA-CBSLR modulates ferroptosis through m6A-YTHDF2-dependent modulation of CBS in gastric cancer
H Yang, Y Hu, M Weng, X Liu, P Wan, Y Hu… - Journal of Advanced …, 2022 - Elsevier
Introduction Tumors are usually refractory to anti-cancer therapeutics under hypoxic
conditions. However, the underlying molecular mechanism remains to be elucidated …
conditions. However, the underlying molecular mechanism remains to be elucidated …
ALKBH5 facilitates hypoxia-induced paraspeckle assembly and IL8 secretion to generate an immunosuppressive tumor microenvironment
The dynamic changes of RNA N6-methyl-adenosine (m6A) during cancer progression
contribute to quick adaption to microenvironmental changes. Here, we profiled the cancer …
contribute to quick adaption to microenvironmental changes. Here, we profiled the cancer …
[HTML][HTML] YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA in hepatocellular carcinoma
L Zhong, D Liao, M Zhang, C Zeng, X Li, R Zhang… - Cancer letters, 2019 - Elsevier
Abstract N 6-methyladenosin (m 6 A) is one of the most pervasive modification of mRNA in
eukaryotes and the m 6 A methyltransferases and demethylases play critical roles in many …
eukaryotes and the m 6 A methyltransferases and demethylases play critical roles in many …
[HTML][HTML] mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
The mechanistic target of rapamycin complex 1 (mTORC1) regulates metabolism and cell
growth in response to nutrient, growth, and oncogenic signals. We found that mTORC1 …
growth in response to nutrient, growth, and oncogenic signals. We found that mTORC1 …
RNA methyltransferase METTL16: Targets and function
ER Satterwhite, KD Mansfield - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Abstract The N6‐methyladenosine (m6A) RNA methyltransferase METTL16 is an emerging
player in the RNA modification landscape of the human cell. Originally thought to be a …
player in the RNA modification landscape of the human cell. Originally thought to be a …
Oxygen radical disease in the newborn, revisited: Oxidative stress and disease in the newborn period
M Perez, ME Robbins, C Revhaug… - Free Radical Biology and …, 2019 - Elsevier
Thirty years ago, there was an emerging appreciation for the significance of oxidative stress
in newborn disease. This prompted a renewed interest in the impact of oxygen therapy for …
in newborn disease. This prompted a renewed interest in the impact of oxygen therapy for …
[HTML][HTML] YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma
Background Dynamic N 6-methyladenosine (m 6 A) modification was previously identified
as a ubiquitous post-transcriptional regulation that affected mRNA homeostasis. However …
as a ubiquitous post-transcriptional regulation that affected mRNA homeostasis. However …
[HTML][HTML] Epitranscriptomic enhancement of influenza A virus gene expression and replication
Many viral RNAs are modified by methylation of the N 6 position of adenosine (m 6 A). m 6 A
is thought to regulate RNA splicing, stability, translation, and secondary structure. Influenza …
is thought to regulate RNA splicing, stability, translation, and secondary structure. Influenza …