Synthesis of Sorafenib− Ruthenium Complexes, Investigation of Biological Activities and Applications in Drug Delivery Systems as an Anticancer Agent
B Zengin Kurt, D Öztürk Civelek… - Journal of Medicinal …, 2024 - ACS Publications
Sorafenib, a multiple kinase inhibitor, is widely used as a first-line treatment for
hepatocellular carcinoma. However, there is a need for more effective alternatives when …
hepatocellular carcinoma. However, there is a need for more effective alternatives when …
Novel 4-((3-fluorobenzyl) oxy) benzohydrazide derivatives as promising anti-prostate cancer agents: Synthesis, characterization and in vitro & in silico biological …
In this study, ten novel halogenated arylidenehydrazide derivatives were synthesized and
characterized through ¹H, ¹³C APT, ¹⁹F NMR, HSQC, HMBC, HRMS, and FT-IR techniques …
characterized through ¹H, ¹³C APT, ¹⁹F NMR, HSQC, HMBC, HRMS, and FT-IR techniques …
Novel complex compounds of nickel with 3-(1-phenyl-2, 3-dimethyl-pyrazolone-5) azopentadione-2, 4: synthesis, NBO analysis, reactivity descriptors and in silico and …
S Tahirli, F Aliyeva, H Şenol… - Journal of …, 2024 - Taylor & Francis
A synthesized azo compound based on 4-amino antipyrine and its complexes with Ni (II) in
solution and solid phase is reported. The structures of these compounds have been testified …
solution and solid phase is reported. The structures of these compounds have been testified …
Synthesis and biological studies of acetophenone-based novel chalcone, semicarbazone, thiosemicarbazone and indolone derivatives: Structure-Activity relationship …
This study presents the synthesis and evaluation of nine acetophenone derivatives (1–9),
with compounds 2, 4, 5, 6, 7, and 9 being novel and synthesized for the first time. These …
with compounds 2, 4, 5, 6, 7, and 9 being novel and synthesized for the first time. These …
Bioactive phenolic contents of Scorzonera ketzkhowelii Sosn. ex Grossh.(Asteraceae) with comprehensive in vitro and in silico studies
This study explores the antioxidant, anti-inflammatory, and anticholinesterase properties of
extracts from the natural plant Scorzonera ketzkhowelii for the first time. Additionally, it …
extracts from the natural plant Scorzonera ketzkhowelii for the first time. Additionally, it …
LC–MS and GC‐MS Analyses on Green Algae Penicillus Capitatus: Cytotoxic, Antimicrobial and Anticholinesterase Activity Screening Enhanced by Molecular …
In this comprehensive screening study, the chemical composition, and cytotoxic,
antimicrobial, and anticholinergic activities of the green algae Penicillus capitatus, collected …
antimicrobial, and anticholinergic activities of the green algae Penicillus capitatus, collected …
Synthesis, biological evaluation, and in silico studies of phenyl naphthalene-2-sulfonate derived thiosemicarbazones as potential carbonic anhydrase inhibitors
A series of novel phenyl naphthalene-2-sulfonate-based thiosemicarbazones (5a-v) were
synthesized and evaluated for their inhibitory activity against human carbonic anhydrases I …
synthesized and evaluated for their inhibitory activity against human carbonic anhydrases I …
Quantitative Determination of the Cytotoxic Compounds in Different Organs of Arctium minus (Hill) Bernh. by LC-HRESIMS Using Respond Survey Methodology
E Erol, KF Erol, RS Yanikoglu, C Taskin… - ACS …, 2024 - ACS Publications
Arctium minus (Hill) Bernh., commonly known as “Burdock”, is a species within the Arctium
genus of the Asteraceae family. Determining the optimum extraction conditions to obtain a …
genus of the Asteraceae family. Determining the optimum extraction conditions to obtain a …
New tetrahydro-isoquinoline derivatives as cholinesterase and α-glycosidase inhibitors: Synthesis, characterization, molecular docking & dynamics, ADME prediction …
In the presented work, it was reported about the synthesis procedure of new isoquinoline
derivatives starting from chalcones and acetoacetanilide, a multi-step synthesis pathway …
derivatives starting from chalcones and acetoacetanilide, a multi-step synthesis pathway …
Synthesis, cytotoxic evaluation, and in silico studies of novel benzenesulfonamide-thiazolidinone derivatives against colorectal carcinoma
Thirteen new benzenesulfonamide derivatives containing 4-thiazolidinone were
synthesized. Their cytotoxic properties were tested on colorectal carcinoma (HT-29, DLD-1 …
synthesized. Their cytotoxic properties were tested on colorectal carcinoma (HT-29, DLD-1 …