Critically ill patients often acquire neuropathy and/or myopathy labeled ICU-acquired
weakness. The current insights into incidence, pathophysiology, diagnostic tools, risk …

Rationale: Diaphragm dysfunction worsens outcomes in mechanically ventilated patients,
but the clinical impact of potentially preventable changes in diaphragm structure and …

Background. To the best of our knowledge, no studies have evaluated the effects of
inspiratory muscle training (IMT) on recovered COVID-19 patients after weaning from …

Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Mechanical ventilation is the most used short-term life support technique worldwide and is
applied daily for a diverse spectrum of indications, from scheduled surgical procedures to …

Diaphragm weakness is highly prevalent in critically ill patients. It may exist prior to ICU
admission and may precipitate the need for mechanical ventilation but it also frequently …

Levosimendan was first approved for clinical use in 2000, when authorization was granted
by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely …

Several mechanisms of diaphragm muscle injury (myotrauma) can result in ventilator-
induced diaphragm dysfunction, including ventilator over-assistance, under-assistance …

We present areas of uncertainty concerning intensive care unit-acquired weakness (ICUAW)
and identify areas for future research. Age, pre-ICU functional and cognitive state …

Rationale: Monitoring and controlling respiratory drive and effort may help to minimize lung
and diaphragm injury. Airway occlusion pressure (P0. 1) is a noninvasive measure of …