Pathogenesis and virulence of herpes simplex virus

S Zhu, A Viejo-Borbolla - Virulence, 2021 - Taylor & Francis
Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

Herpes simplex virus infections

RJ Whitley, B Roizman - The lancet, 2001 - thelancet.com
Herpes simplex virus (HSV) is a member of the herpesviridae family. Recognised since
ancient Greek times, the virus frequently infects human beings, causing a range of diseases …

[HTML][HTML] The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells

WR Heath, FR Carbone - Nature immunology, 2013 - nature.com
The skin is a highly complex organ interspersed with a variety of smaller organ-like
structures and a plethora of cell types that together perform essential functions such as …

Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review

JS Smith, NJ Robinson - The Journal of infectious diseases, 2002 - academic.oup.com
Abstract Information on age-and sex-specific prevalence of herpes simplex virus (HSV)
types 2 and 1 infections is essential to optimize genital herpes control strategies, which …

Tissue‐resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance

T Gebhardt, U Palendira, DC Tscharke… - Immunological …, 2018 - Wiley Online Library
A large proportion of memory T cells disseminated throughout the body are non‐
recirculating cells whose maintenance and function is regulated by tissue‐specific …

Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management

M Fatahzadeh, RA Schwartz - Journal of the American Academy of …, 2007 - Elsevier
Eight of the more than 80 known herpesviruses are human pathogens. Human herpes
simplex virus (HSV) is a contagious infection with a large reservoir in the general population …

Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant

ZA Brown, A Wald, RA Morrow, S Selke, J Zeh, L Corey - Jama, 2003 - jamanetwork.com
Context Neonatal herpes most commonly results from fetal exposure to infected maternal
genital secretions at the time of delivery. The risk of transmission from mother to infant as it …

Once-daily valacyclovir to reduce the risk of transmission of genital herpes

L Corey, A Wald, R Patel, SL Sacks… - … England Journal of …, 2004 - Mass Medical Soc
Background Nucleoside analogues against herpes simplex virus (HSV) have been shown to
suppress shedding of HSV type 2 (HSV-2) on genital mucosal surfaces and may prevent …

The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: a review of two overlapping epidemics

L Corey, A Wald, CL Celum… - JAIDS Journal of Acquired …, 2004 - journals.lww.com
Increasing evidence demonstrates a substantial link between the epidemics of sexually
transmitted HIV-1 and herpes simplex virus (HSV)-2 infection. More than 30 epidemiologic …

Reactivation of genital herpes simplex virus type 2 infection in asymptomatic seropositive persons

A Wald, J Zeh, S Selke, T Warren… - … England Journal of …, 2000 - Mass Medical Soc
Background Most persons who have serologic evidence of infection with herpes simplex
virus (HSV) type 2 (HSV-2) are asymptomatic. Historically, it has been assumed that these …