Major depressive disorder

W Marx, BWJH Penninx, M Solmi… - Nature Reviews …, 2023 - nature.com
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

[HTML][HTML] Advances in problematic usage of the internet research–A narrative review by experts from the European network for problematic usage of the internet

NA Fineberg, JM Menchón, N Hall, B Dell'Osso… - Comprehensive …, 2022 - Elsevier
Global concern about problematic usage of the internet (PUI), and its public health and
societal costs, continues to grow, sharpened in focus under the privations of the COVID-19 …

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

AS Hatoum, SMC Colbert, EC Johnson… - Nature Mental …, 2023 - nature.com
Genetic liability to substance use disorders can be parsed into loci that confer general or
substance-specific addiction risk. We report a multivariate genome-wide association meta …

Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes

M Ribasés, M Mitjans, CA Hartman, MS Artigas… - Neuroscience & …, 2023 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …

Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder

FR Wendt, GA Pathak, JD Deak, F De Angelis… - Molecular …, 2022 - nature.com
UK Biobank (UKB) is a key contributor in mental health genome-wide association studies
(GWAS) but only~ 31% of participants completed the Mental Health Questionnaire (“MHQ …

[HTML][HTML] Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality

FR Wendt, GA Pathak, DF Levey, YZ Nuñez… - Neurobiology of …, 2021 - Elsevier
Epidemiologic studies recognize that trauma and posttraumatic stress are associated with
heightened suicidal behavior severity, yet examination of these associations from a genetic …

The multiple mediating effect of family health and perceived social support on depressive symptoms in older adults: A cross-sectional national survey in China

R Hao, H Jin, J Zuo, Y Wu, X Sun, J Hu - Journal of Affective Disorders, 2023 - Elsevier
Background Depression harms older adults' physical health and quality of life, especially for
those with disabilities. This study aims to investigate the epidemiological characteristics of …

The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes

BL Mitchell, AI Campos, DC Whiteman, CM Olsen… - Biological …, 2022 - Elsevier
Background Major depressive disorder (MDD) is a common and highly heterogeneous
psychiatric disorder, but little is known about the genetic characterization of this …

What next for eating disorder genetics? Replacing myths with facts to sharpen our understanding

LM Huckins, R Signer, J Johnson, YK Wu… - Molecular …, 2022 - nature.com
Substantial progress has been made in the understanding of anorexia nervosa (AN) and
eating disorder (ED) genetics through the efforts of large-scale collaborative consortia …

Characterizing the longitudinal course of symptoms and functioning in bipolar disorder

KM Mignogna, FS Goes - Psychological medicine, 2024 - cambridge.org
BackgroundThe course of Bipolar Disorder (BD) is highly variable, with marked inter and
intra-individual differences in symptoms and functioning. In this study, we identified illness …