Dysphagia is a common symptom with significant impact on quality of life. Our diagnostic
armamentarium was primarily limited to endoscopy and barium esophagram until the advent …

Aim To systematically review clinical presentation, diagnosis, and therapy of achalasia,
focusing on recent developments in high-resolution esophageal manometry (HREM) for …

Background and study aims Peroral endoscopic myotomy (POEM) can be performed via an
anterior or posterior approach, depending on the operator's preference. Data are lacking on …

Background Primary and secondary peristalsis facilitate esophageal bolus transport;
however, their relative impact for bolus clearance remains unclear. We aimed to compare …

Background and Aims The symptoms of reflux in achalasia patients undergoing peroral
endoscopic myotomy (POEM) are believed to result from gastroesophageal reflux, and the …

Achalasia is a major esophageal motor disorder featured by the altered relaxation of the
esophagogastric junction in the absence of effective peristaltic activity. As a consequence of …

Objective. Per-oral endoscopic myotomy (POEM) has recently been introduced as a minimal
invasive alternative to conventional treatment for achalasia. This study aimed to clarify the …

A precise diagnosis is key to the successful treatment of achalasia. Barium swallow, upper
endoscopy and high-resolution manometry provide the necessary information about a …

Achalasia is a rare motility disorder with incomplete relaxation of the lower esophageal
sphincter and ineffective contractions of the esophageal body. It has been hypothesized that …

Achalasia is a rare esophageal motor disorder characterized by abnormal or absent
peristalsis associated with incomplete relaxation of the lower esophageal sphincter (LES) …