[HTML][HTML] Schwann cells are key regulators of corneal epithelial renewal

K Mirmoeini, K Tajdaran, J Zhang… - … & Visual Science, 2023 - tvst.arvojournals.org
Purpose: Corneal sensory nerves protect the cornea from injury. They are also thought to
stimulate limbal stem cells (LSCs) to produce transparent epithelial cells constantly …

Developmental malformations resulting from high-dose maternal tamoxifen exposure in the mouse

MR Sun, AC Steward, EA Sweet, AA Martin… - PLoS …, 2021 - journals.plos.org
Tamoxifen is an estrogen receptor (ER) ligand with widespread use in clinical and basic
research settings. Beyond its application in treating ER-positive cancer, tamoxifen has been …

Sacral neural crest-independent origin of the enteric nervous system in mouse

Q Yu, L Liu, M Du, D Müller, Y Gu, Z Gao, X Xin, Y Gu… - Gastroenterology, 2024 - Elsevier
Background & Aims The enteric nervous system (ENS), the gut's intrinsic nervous system
critical for gastrointestinal function and gut-brain communication, is believed to mainly …

[HTML][HTML] Altered sacral neural crest development in Pax3 spina bifida mutants underlies deficits of bladder innervation and function

KK Deal, AS Chandrashekar, MM Beaman… - Developmental …, 2021 - Elsevier
Mouse models of Spina bifida (SB) have been instrumental for identifying genes,
developmental processes, and environmental factors that influence neurulation and neural …

Multiple congenital malformations arise from somatic mosaicism for constitutively active Pik3ca signaling

E Marechal, A Poliard, K Henry, M Moreno… - Frontiers in Cell and …, 2022 - frontiersin.org
Recurrent missense mutations of the PIK3CA oncogene are among the most frequent
drivers of human cancers. These often lead to constitutive activation of its product p110α, a …