Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

Chargé, Sophie BP, and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle
Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev. 00019.2003.—Under …

Muscle regeneration requires the coordinated interaction of multiple cell types. Satellite cells
have been implicated as the primary stem cell responsible for regenerating muscle, yet the …

Macrophages (MPs) are important for skeletal muscle regeneration in vivo and may exert
beneficial effects on myogenic cell growth through mitogenic and antiapoptotic activities in …

The fusion of myoblasts into multinucleate syncytia plays a fundamental role in muscle
function, as it supports the formation of extended sarcomeric arrays, or myofibrils, within a …

Adult skeletal muscle has a remarkable ability to regenerate following myotrauma. Because
adult myofibers are terminally differentiated, the regeneration of skeletal muscle is largely …

Muscle injuries are one of the most common traumas occurring in sports. Despite their
clinical importance, few clinical studies exist on the treatment of these traumas. Thus, the …

Skeletal muscle continuously adapts to changes in its mechanical environment through
modifications in gene expression and protein stability that affect its physiological function …

Once escaped from the quiescence niche, precursor cells interact with stromal components
that support their survival, proliferation, and differentiation. We examined interplays between …

Transforming growth factor-β1 (TGF-β1) is thought to play a crucial role in fibrotic diseases.
This study demonstrates for the first time that TGF-β1 stimulation can induce myoblasts …