Adults with Down syndrome develop the neuropathological hallmarks of Alzheimer's
disease and are at very high risk of developing early-onset dementia, which is now the …

Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …

Down syndrome (DS) is a genetic disease that occurs due to an aneuploidy of human
chromosome 21. Trisomy of chromosome 21 is a primary genetic cause of developmental …

Background Dementia in people with intellectual disability (ID) is frequent but hard to
recognise. Evidence-based recommendations for suitable instruments are lacking. Aims The …

Down syndrome arises from chromosomal non-disjunction during gametogenesis, resulting
in an additional chromosome. This anomaly presents with intellectual impairment, growth …

Down Syndrome (DS) is the most common genetic cause of intellectual disability in which
delays and impairments in brain development and function lead to neurological and …

Background Dementia is increasingly prevalent in people with severe/profound intellectual
disabilities. However, early detection and diagnosis of dementia is complex in this …

Background People with intellectual disabilities are more likely to experience sleep
problems, which can affect quality of life, physical health, mental health and well‐being …

Background An estimated 1.5 million persons in Germany are intellectually disabled.
Persons with intellectual disability (ID) are especially vulnerable to somatic and mental …

Background Differentiating dementia from baseline level of functioning is difficult among
people with severe/profound intellectual (and multiple) disabilities. Moreover, studies on …