Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …

Whether the lipid profile in diabetic patients is associated with diabetic neuropathy (DN)
development remains ambiguous, as does the predictive value of serum lipid levels in the …

Aims/hypothesis The individual risk of progression of diabetic peripheral neuropathy is
difficult to predict for each individual. Mutations in proteins that are responsible for the …

Hyperlipidaemia, particularly hypertriglyceridemia, is associated with the development and
progression of neuropathy. Lipid modifying agents may represent a potential therapeutic …

We have reviewed the genetic basis of chylomicronaemia, the difference between
monogenic and polygenic hypertriglyceridaemia, its effects on pancreatic, cardiovascular …

Importance Lowering serum cholesterol levels is a well-established treatment for
dyslipidemia in patients with type 2 diabetes (T2D). However, nerve lesions in patients with …

Background Nerve damage in diabetic neuropathy (DN) is assumed to begin in the distal
legs with a subsequent progression to hands and arms at later stages. In contrast, recent …