It is now little disputed that most if not all cancer cells express antigens that can be
recognized by specific CD8+ T lymphocytes. However, a central question in the field of anti …

Immunotherapy (IO) has revolutionized the therapy landscape of non-small cell lung cancer
(NSCLC), significantly prolonging the overall survival (OS) of advanced stage patients. Over …

Purpose: The major value of prognostic markers in potentially curable non-small cell lung
cancer (NSCLC) should be to guide therapy after surgical resection. In this regard, the …

T-cell-secreted interferon (IFN)-γ can exert pleiotropic effects on tumor cells that include
induction of immune checkpoints and antigen presentation machinery components, and …

Background The clinical efficacy observed with inhibitors of programed cell death
1/programed cell death ligand 1 (PD-L1/PD-1) in cancer therapy has prompted studies to …

We previously identified three novel HLA‐A24‐restricted epitope peptides, which were
derived from three cancer‐testis antigens, TTK protein kinase (TTK), lymphocyte antigen 6 …

Tumor-associated lymphatic vessels promote metastasis and regulate antitumor immune
responses. Here, we assessed the impact of cytotoxic T cells on the local lymphatic …

Targeting cancer cells, as well as the nonmalignant stromal cells cross-presenting the tumor
antigen (Ag), can lead to the complete destruction of well-established solid tumors by …

Relapse after autologous or allogeneic hematopoietic stem cell transplantation has become
the most frequent cause of treatment failure. The third International Workshop on Biology …

The identification of tumor-expressed antigens that can be recognized by specific T
lymphocytes has made it possible both to study the properties of T cells participating in anti …