[HTML][HTML] The role of lung and gut microbiota in the pathology of asthma
Asthma is a common chronic respiratory disease affecting more than 300 million people
worldwide. Clinical features of asthma and its immunological and molecular etiology vary …
worldwide. Clinical features of asthma and its immunological and molecular etiology vary …
Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
[HTML][HTML] Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
KL Bowerman, SF Rehman, A Vaughan… - Nature …, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is the third commonest cause of death
globally, and manifests as a progressive inflammatory lung disease with no curative …
globally, and manifests as a progressive inflammatory lung disease with no curative …
Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions
Z Yan, B Chen, Y Yang, X Yi, M Wei… - Nature …, 2022 - nature.com
The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …
[HTML][HTML] Dysbiosis of the gut and lung microbiome has a role in asthma
K Hufnagl, I Pali-Schöll, F Roth-Walter… - Seminars in …, 2020 - Springer
Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …
asthma is influenced by environmental and other exogenous factors synergizing with …
Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention
E von Mutius, HH Smits - The Lancet, 2020 - thelancet.com
Asthma is a complex disease that often starts in childhood. Genomic and environmental
factors as well as aberrant immune maturation early in life can contribute to the onset of …
factors as well as aberrant immune maturation early in life can contribute to the onset of …
[HTML][HTML] Integrative microbiomics in bronchiectasis exacerbations
M Mac Aogain, JK Narayana, PY Tiew, NABM Ali… - Nature medicine, 2021 - nature.com
Bronchiectasis, a progressive chronic airway disease, is characterized by microbial
colonization and infection. We present an approach to the multi-biome that integrates …
colonization and infection. We present an approach to the multi-biome that integrates …
Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease
W Liang, Y Yang, S Gong, M Wei, Y Ma, R Feng… - Cell host & …, 2023 - cell.com
Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease
(COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression …
(COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression …
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis
Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …
[HTML][HTML] Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
Background Chronic airway inflammation is the main driver of pathogenesis in respiratory
diseases such as severe asthma, chronic obstructive pulmonary disease, cystic fibrosis (CF) …
diseases such as severe asthma, chronic obstructive pulmonary disease, cystic fibrosis (CF) …