Aging is a major risk factor for numerous human pathologies, including cardiovascular,
metabolic, musculoskeletal, and neurodegenerative conditions and various malignancies …

AMP-activated protein kinase (AMPK) is a ubiquitous sensor of energy and nutritional status
in eukaryotic cells. It plays a key role in regulating cellular energy homeostasis and multiple …

Metabolic reprogramming is a unique but complex biochemical adaptation that allows solid
tumors to tolerate various stresses that challenge cancer cells for survival. Under conditions …

Cancer is a serious public health problem in the world and a major disease affecting human
health. Dietary polyphenols have shown good potential in the treatment of various cancers. It …

The development of white adipose tissue (WAT) browning helps to protect animals from cold
conditions and prevent obesity. AMPKα1 has been involved in the process of white …

Purpose Colorectal cancer (CRC) is the third most common cancer, and the second leading
cause of cancer death worldwide. Dysregulation of microRNAs has been shown to modulate …

Macrophages are critical effector cells of the innate immune system. The presence of
microbes or the stimulation by inflammatory factors triggers the metabolic reprogramming of …

Simple Summary Probiotics, beneficial bacteria that contribute to the health of both humans
and animals, play a crucial role in aquaculture by enhancing digestion and bolstering …

Upon chronic stress, β-adrenergic receptor activation induces cardiac fibrosis and leads to
heart failure. The small molecule compound IMM-H007 has demonstrated protective effects …

Purpose Hypertensive disorder complicating pregnancy (HDCP) is a serious clinical
disorder syndrome during pregnancy. This study aims at finding novel targets for HDCP …