Endocytosis allows cells to transport particles and molecules across the plasma membrane.
In addition, it is involved in the termination of signalling through receptor downmodulation …

Angiogenesis is defined as a new blood vessel sprouting from pre-existing vessels. This
highly regulated process take place through two non-exclusive events, the so-called …

To form epithelial organs cells must polarize and generate de novo an apical domain and
lumen. Epithelial polarization is regulated by polarity complexes that are hypothesized to …

The formation of epithelial tissues containing lumens requires not only the apical-basolateral
polarization of cells, but also the coordinated orientation of this polarity such that the apical …

Tissues use numerous mechanisms to change shape during development. The Drosophila
egg chamber is an organ-like structure that elongates to form an elliptical egg. During …

Polarized epithelial cells have a distinctive apical–basal axis of polarity for vectorial
transport of ions and solutes across the epithelium. In contrast, migratory mesenchymal cells …

The asymmetric polarization of cells allows specialized functions to be performed at discrete
subcellular locales. Spatiotemporal coordination of polarization between groups of cells …

Cells can migrate individually or collectively. Collective movement is common during normal
development and is also a characteristic of some cancers. This review discusses recent …

Many organs contain networks of epithelial tubes that transport gases or fluids. A lumen can
be generated by tissue that enwraps a pre-existing extracellular space or it can arise de …

Background Organoids are morphologically heterogeneous three-dimensional cell culture
systems and serve as an ideal model for understanding the principles of collective cell …