Endocytosis in the context-dependent regulation of individual and collective cell properties
S Sigismund, L Lanzetti, G Scita… - Nature Reviews Molecular …, 2021 - nature.com
Endocytosis allows cells to transport particles and molecules across the plasma membrane.
In addition, it is involved in the termination of signalling through receptor downmodulation …
In addition, it is involved in the termination of signalling through receptor downmodulation …
[HTML][HTML] “Sprouting angiogenesis”, a reappraisal
D Ribatti, E Crivellato - Developmental biology, 2012 - Elsevier
Angiogenesis is defined as a new blood vessel sprouting from pre-existing vessels. This
highly regulated process take place through two non-exclusive events, the so-called …
highly regulated process take place through two non-exclusive events, the so-called …
A molecular network for de novo generation of the apical surface and lumen
To form epithelial organs cells must polarize and generate de novo an apical domain and
lumen. Epithelial polarization is regulated by polarity complexes that are hypothesized to …
lumen. Epithelial polarization is regulated by polarity complexes that are hypothesized to …
[HTML][HTML] A molecular switch for the orientation of epithelial cell polarization
The formation of epithelial tissues containing lumens requires not only the apical-basolateral
polarization of cells, but also the coordinated orientation of this polarity such that the apical …
polarization of cells, but also the coordinated orientation of this polarity such that the apical …
[HTML][HTML] Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation
Tissues use numerous mechanisms to change shape during development. The Drosophila
egg chamber is an organ-like structure that elongates to form an elliptical egg. During …
egg chamber is an organ-like structure that elongates to form an elliptical egg. During …
Remodeling epithelial cell organization: transitions between front–rear and apical–basal polarity
WJ Nelson - Cold Spring Harbor perspectives in biology, 2009 - cshperspectives.cshlp.org
Polarized epithelial cells have a distinctive apical–basal axis of polarity for vectorial
transport of ions and solutes across the epithelium. In contrast, migratory mesenchymal cells …
transport of ions and solutes across the epithelium. In contrast, migratory mesenchymal cells …
[HTML][HTML] Molecular regulation of lumen morphogenesis
The asymmetric polarization of cells allows specialized functions to be performed at discrete
subcellular locales. Spatiotemporal coordination of polarization between groups of cells …
subcellular locales. Spatiotemporal coordination of polarization between groups of cells …
Fellow travellers: emergent properties of collective cell migration
P Rørth - EMBO reports, 2012 - embopress.org
Cells can migrate individually or collectively. Collective movement is common during normal
development and is also a characteristic of some cancers. This review discusses recent …
development and is also a characteristic of some cancers. This review discusses recent …
Molecular mechanisms of de novo lumen formation
S Sigurbjörnsdóttir, R Mathew, M Leptin - Nature reviews Molecular cell …, 2014 - nature.com
Many organs contain networks of epithelial tubes that transport gases or fluids. A lumen can
be generated by tissue that enwraps a pre-existing extracellular space or it can arise de …
be generated by tissue that enwraps a pre-existing extracellular space or it can arise de …
[HTML][HTML] Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis
L Hof, T Moreth, M Koch, T Liebisch, M Kurtz, J Tarnick… - BMC biology, 2021 - Springer
Background Organoids are morphologically heterogeneous three-dimensional cell culture
systems and serve as an ideal model for understanding the principles of collective cell …
systems and serve as an ideal model for understanding the principles of collective cell …