Drug resistance in influenza A virus: the epidemiology and management

M Hussain, HD Galvin, TY Haw… - Infection and drug …, 2017 - Taylor & Francis
Influenza A virus (IAV) is the sole cause of the unpredictable influenza pandemics and
deadly zoonotic outbreaks and constitutes at least half of the cause of regular annual …

Clinical implications of antiviral resistance in influenza

TCM Li, MCW Chan, N Lee - Viruses, 2015 - mdpi.com
Influenza is a major cause of severe respiratory infections leading to excessive
hospitalizations and deaths globally; annual epidemics, pandemics, and sporadic/endemic …

Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives

AC Hurt, T Chotpitayasunondh, NJ Cox… - The Lancet infectious …, 2012 - thelancet.com
Summary Influenza A H1N1 2009 virus caused the first pandemic in an era when
neuraminidase inhibitor antiviral drugs were available in many countries. The experiences …

Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition

CJ Vavricka, Q Li, Y Wu, J Qi, M Wang, Y Liu… - PLoS …, 2011 - journals.plos.org
The 2009 H1N1 influenza pandemic (pH1N1) led to record sales of neuraminidase (NA)
inhibitors, which has contributed significantly to the recent increase in oseltamivir-resistant …

Update on influenza diagnostics: lessons from the novel H1N1 influenza A pandemic

S Kumar, KJ Henrickson - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The menu of diagnostic tools that can be utilized to establish a diagnosis of influenza is
extensive and includes classic virology techniques as well as new and emerging methods …

Influenza: epidemiology, clinical features, therapy, and prevention

NM Clark, JP Lynch - Seminars in respiratory and critical care …, 2011 - thieme-connect.com
Influenza A and B are important causes of respiratory illness in all age groups. Influenza
causes seasonal outbreaks globally and, less commonly, pandemics. In the United States …

Preclinical and clinical developments for combination treatment of influenza

P Koszalka, K Subbarao, M Baz - PLoS Pathogens, 2022 - journals.plos.org
Antiviral drugs are an important measure of control for influenza in the population,
particularly for those that are severely ill or hospitalised. The neuraminidase inhibitor (NAI) …

Antivirals targeting the surface glycoproteins of influenza virus: Mechanisms of action and resistance

Y Bai, JC Jones, SS Wong, M Zanin - Viruses, 2021 - mdpi.com
Hemagglutinin and neuraminidase, which constitute the glycoprotein spikes expressed on
the surface of influenza A and B viruses, are the most exposed parts of the virus and play …

Does respiratory virus coinfection increases the clinical severity of acute respiratory infection among children infected with respiratory syncytial virus?

Y Harada, F Kinoshita, LM Yoshida… - The Pediatric …, 2013 - journals.lww.com
Background: Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory
infection in children less than 5 years of age. The impact of non-RSV respiratory virus …

Aronia melanocarpa and its components demonstrate antiviral activity against influenza viruses

S Park, JI Kim, I Lee, S Lee, MW Hwang, JY Bae… - Biochemical and …, 2013 - Elsevier
The influenza virus is highly contagious in human populations around the world and results
in approximately 250,000–500,000 deaths annually. Vaccines and antiviral drugs are …