Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Emerging evidence has shown that microRNAs (miRNAs) play essential roles in regulating
human cancers development and progression. However, the underlying mechanisms …

Breast cancer is the second-most common cancer and second-leading cause of cancer
mortality in American women. The dysregulation of microRNAs (miRNAs) plays a key role in …

The methylation of promoter CpG islands and the interaction between microRNAs (miRNAs)
and messenger RNAs (mRNAs) of target genes are considered two crucial mechanisms for …

Dysregulation of long non-codng RNA (lncRNA) expression has been found to contribute to
tumorigenesis. However, the roles of lncRNAs in BRCA1-related breast cancer remain …

Methylation of promoter CpG islands may suppress the function of miRNAs by inhibiting their
expression. Our work analyzes the role of promoter methylation in altering the expression of …

Accumulating evidence indicates that microRNAs can regulate the apoptosis of various
cells. Apoptosis of nucleus pulposus cells plays an important role in the progression of …

An increasing number of studies indicate that microRNAs (miRNAs/miRs) are involved in
diverse biological signaling pathways and play important roles in the progression of various …

MicroRNAs play an important role in the regulation of expression of many genes involved in
cancer pathogenesis. One of the causes of miRNA level deregulation in tumors is the …

Background Light quality severely affects biosynthesis and metabolism-associated process
of glutathione. However, the role of specific light is still unclear on the glutathione …