Two-component FAD-dependent monooxygenases: current knowledge and biotechnological opportunities

T Heine, WJH Van Berkel, G Gassner, KH Van Pée… - Biology, 2018 - mdpi.com
Flavoprotein monooxygenases create valuable compounds that are of high interest for the
chemical, pharmaceutical, and agrochemical industries, among others. Monooxygenases …

A review: the styrene metabolizing cascade of side-chain oxygenation as biotechnological basis to gain various valuable compounds

M Oelschlägel, J Zimmerling, D Tischler - Frontiers in microbiology, 2018 - frontiersin.org
Styrene is one of the most produced and processed chemicals worldwide and is released
into the environment during widespread processing. But, it is also produced from plants and …

The taming of oxygen: biocatalytic oxyfunctionalisations

D Holtmann, MW Fraaije, IWCE Arends… - Chemical …, 2014 - pubs.rsc.org
Selective oxyfunctionalisation of non-activated hydrocarbons represents a contemporary
issue of organic chemistry. The inertness of most C–H bonds requires powerful oxygen …

Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and …

J Kratky, D Eggerichs, T Heine… - Angewandte Chemie …, 2023 - Wiley Online Library
Flavoprotein monooxygenases are a versatile group of enzymes for biocatalytic
transformations. Among these, group E monooxygenases (GEMs) catalyze enantioselective …

The versatility of non-heme diiron monooxygenase PmlABCDEF: a single biocatalyst for a plethora of oxygenation reactions

V Petkevičius, J Vaitekūnas, M Sadauskas… - Catalysis Science & …, 2022 - pubs.rsc.org
In this paper, we discuss the application of the non-heme diiron monooxygenase
PmlABCDEF and its mutants in a variety of different oxidation reactions. Whole cells of …

Catalytic and structural features of flavoprotein hydroxylases and epoxidases

S Montersino, D Tischler, GT Gassner… - Advanced Synthesis …, 2011 - Wiley Online Library
Monooxygenases perform chemo‐, regio‐and/or enantioselective oxygenations of organic
substrates under mild reaction conditions. These properties and the increasing number of …

Chemoenzymatic epoxidation of alkenes with Candida antarctica lipase B and hydrogen peroxide in deep eutectic solvents

P Zhou, X Wang, B Yang, F Hollmann, Y Wang - RSC advances, 2017 - pubs.rsc.org
Epoxides are important synthetic intermediates for the synthesis of a broad range of
industrial products. This study presents a promising solution to the current limitation of …

Biocatalysis as an alternative for the production of chiral epoxides: a comparative review

H Lin, JY Liu, HB Wang, AAQ Ahmed, ZL Wu - Journal of Molecular …, 2011 - Elsevier
Enantiopure epoxides are remarkably versatile intermediates for the synthesis of numerous
biologically active targets, to which considerable efforts have been devoted either …

Nonconventional regeneration of redox enzymes–a practical approach for organic synthesis?

W Zhang, F Hollmann - Chemical Communications, 2018 - pubs.rsc.org
Oxidoreductases have become useful tools in the hands of chemists to perform selective
and mild oxidation and reduction reactions. Instead of mimicking native catalytic cycles …

Biodiversity of microorganisms colonizing the surface of polystyrene samples exposed to different aqueous environments

T Tourova, D Sokolova, T Nazina, D Grouzdev… - Sustainability, 2020 - mdpi.com
The contamination of marine and freshwater ecosystems with the items from thermoplastics,
including polystyrene (PS), necessitates the search for efficient microbial degraders of these …