The high osmolarity glycerol (HOG) pathway in fungi

H Yaakoub, NS Sanchez, L Ongay-Larios… - Critical Reviews in …, 2022 - Taylor & Francis
While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …

Every road leads to Rome: diverse biosynthetic regulation of plant cell wall-degrading enzymes in filamentous fungi Penicillium oxalicum and Trichoderma reesei

S Zhao, T Zhang, T Hasunuma, A Kondo… - Critical Reviews in …, 2024 - Taylor & Francis
Cellulases and xylanases are plant cell wall-degrading enzymes (CWDEs) that are critical to
sustainable bioproduction based on renewable lignocellulosic biomass to reduce carbon …

Phosphosite scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1

MM Conti, R Li, MA Narváez Ramos, LJ Zhu… - Nature …, 2023 - nature.com
Ordered cell cycle progression is coordinated by cyclin dependent kinases (CDKs). CDKs
often phosphorylate substrates at multiple sites clustered within disordered regions …

Repression of essential cell cycle genes increases cellular fitness

MM Conti, JM Ghizzoni, A Gil-Bona, W Wang… - PLoS …, 2022 - journals.plos.org
A network of transcription factors (TFs) coordinates transcription with cell cycle events in
eukaryotes. Most TFs in the network are phosphorylated by cyclin-dependent kinase (CDK) …

CRZ1 transcription factor is involved in cell survival, stress tolerance, and virulence in fungi

S Gupta, A Kumar, R Tamuli - Journal of Biosciences, 2022 - Springer
The calcineurin-CRZ1 signaling pathway is conserved from yeasts to humans, and is
involved in survival, tolerance to biotic and abiotic stress conditions, virulence, and drug …

The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis

J Jiménez, E Queralt, F Posas, E de Nadal - Cell Cycle, 2020 - Taylor & Francis
During evolution, cells have developed a plethora of mechanisms to optimize survival in a
changing and unpredictable environment. In this regard, they have evolved networks that …

Involvement of the high-osmolarity glycerol pathway of Saccharomyces cerevisiae in protection against copper toxicity

M Ren, R Li, B Han, Y You, W Huang, G Du, J Zhan - Antioxidants, 2022 - mdpi.com
Although essential for life, copper is also potentially toxic in concentrations that surpass
physiological thresholds. The high-osmolarity glycerol pathway of yeast is the main regulator …

The MAP kinase FvHog1 regulates FB1 synthesis and Ca2+ homeostasis in Fusarium verticillioides

H Xia, X Xia, M Guo, W Liu, G Tang - Journal of Hazardous Materials, 2024 - Elsevier
The high osmolarity glycerol 1 mitogen-activated protein kinase (Hog1-MAPK) cascade
genes are important for diverse biological processes. The activated Hog1 upon multiple …

S mall M olecule Ar ranged T hermal P roximity C oa ggregation (smarTPCA)—A Novel Approach to Characterize Protein–Protein Interactions in Living Cells by …

T Lenz, K Stühler - International Journal of Molecular Sciences, 2022 - mdpi.com
Chemical biology and the application of small molecules has proven to be a potent
perturbation strategy, especially for the functional elucidation of proteins, their networks, and …

Identification of genes associated with abiotic stress tolerance in sweetpotato using weighted gene co‐expression network analysis

M Kitavi, DC Gemenet, JC Wood, JP Hamilton… - Plant …, 2023 - Wiley Online Library
Abstract Sweetpotato, Ipomoea batatas (L.), a key food security crop, is negatively impacted
by heat, drought, and salinity stress. The orange‐fleshed sweetpotato cultivar “Beauregard” …