Antimicrobial peptides: mechanism of action, activity and clinical potential
QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
Antimicrobial peptides and copper (II) ions: Novel therapeutic opportunities
J Portelinha, SS Duay, SI Yu, K Heilemann… - Chemical …, 2021 - ACS Publications
The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …
health issue that requires the development of novel classes of antibiotics. Antimicrobial …
Antibiotic-peptide conjugation against multi-drug resistant pathogens: a comprehensive review for therapeutics and drug delivery strategies
K Kalimuthu, NR Srinivasan… - International Journal of …, 2023 - Springer
A global public health crisis has been created by the emergence of serious infectious
illnesses, the rising prevalence of infections that are impenetrable to antibiotics (AMR), and …
illnesses, the rising prevalence of infections that are impenetrable to antibiotics (AMR), and …
Incorporation of β‐Alanine in Cu (II) ATCUN Peptide Complexes Increases ROS Levels, DNA Cleavage and Antiproliferative Activity
J Heinrich, K Bossak‐Ahmad, M Riisom… - … A European Journal, 2021 - Wiley Online Library
Redox‐active Cu (II) complexes are able to form reactive oxygen species (ROS) in the
presence of oxygen and reducing agents. Recently, Faller et al. reported that ROS …
presence of oxygen and reducing agents. Recently, Faller et al. reported that ROS …
Synthesis and characterization of cobalt (II) pincer complexes and their application as dyes in dye-sensitized solar cells
A series of eight cobalt (II) pincer complexes were prepared by using NNN tridentate and NN
bidentate pincer ligand systems. All the ligands and complexes were completely …
bidentate pincer ligand systems. All the ligands and complexes were completely …
Head-to-head bisbenzazole derivatives as antiproliferative agents: design, synthesis, in vitro activity, and SAR analysis
RH Ersan, MA Alagoz, T Ertan-Bolelli, N Duran… - Molecular Diversity, 2021 - Springer
In the present work, a series of bisbenzazole derivatives were designed and synthesized as
antiproliferative agents. The antiproliferative activity of these compounds was investigated …
antiproliferative agents. The antiproliferative activity of these compounds was investigated …
[HTML][HTML] Gold (III) complexes with thiosemicarbazone ligands: insights into their cytotoxic effects on lung cancer cells
M Scaccaglia, S Pinelli, L Manini, B Ghezzi… - Journal of Inorganic …, 2024 - Elsevier
Cancer continues to pose a global threat, underscoring the urgent need for more effective
and safer treatment options. Gold-based compounds have recently emerged as promising …
and safer treatment options. Gold-based compounds have recently emerged as promising …
Benzimidazole-quinoline-based copper complexes: Exploration for their possible antitumor mechanism
J Hu, T Cao, B Yuan, Y Guo, J Zhang, X Zhao, H Hou - Polyhedron, 2022 - Elsevier
In this study, we synthesised and characterised two benzimidazole-quinoline-based copper
complexes, namely,[Cu (btmbq) Br] 2 (1) and [Cu (btmbq) Cl] 2 (2),(btmbq= 3-(1-(1H …
complexes, namely,[Cu (btmbq) Br] 2 (1) and [Cu (btmbq) Cl] 2 (2),(btmbq= 3-(1-(1H …
Nuclease-like metalloscissors: Biomimetic candidates for cancer and bacterial and viral infections therapy
M Anjomshoa, B Amirheidari - Coordination Chemistry Reviews, 2022 - Elsevier
Despite the extensive and rapid discovery of modern drugs for treatment of cancer, microbial
infections, and viral illnesses; these diseases are still among major global health concerns …
infections, and viral illnesses; these diseases are still among major global health concerns …
Two new lanthanide complexes with 5-(Pyrazol-1-yl) nicotinic acid: Structures and their anti-cancer properties
X Zhu, Z Li, X Ji, Q Chen, S Wu, E Gao, M Zhu - Journal of Inorganic …, 2021 - Elsevier
Two new lanthanide complexes [PrL 2 (EA) 2] NO 3 (complex 1) and [SmL 2 (EA) 2] NO 3
(complex 2)(H 2 L= 5-(Pyrazol-1-yl) nicotinic acid, EA= CH 3 CH 2 OH) were synthesized …
(complex 2)(H 2 L= 5-(Pyrazol-1-yl) nicotinic acid, EA= CH 3 CH 2 OH) were synthesized …