Molecular mechanisms of dietary restriction promoting health and longevity

CL Green, DW Lamming, L Fontana - Nature Reviews Molecular Cell …, 2022 - nature.com
Dietary restriction with adequate nutrition is the gold standard for delaying ageing and
extending healthspan and lifespan in diverse species, including rodents and non-human …

Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Exercise metabolism and adaptation in skeletal muscle

JAB Smith, KA Murach, KA Dyar… - Nature Reviews Molecular …, 2023 - nature.com
Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Skeletal muscle energy metabolism during exercise

M Hargreaves, LL Spriet - Nature metabolism, 2020 - nature.com
The continual supply of ATP to the fundamental cellular processes that underpin skeletal
muscle contraction during exercise is essential for sports performance in events lasting …

Hallmarks of health

C López-Otín, G Kroemer - Cell, 2021 - cell.com
Health is usually defined as the absence of pathology. Here, we endeavor to define health
as a compendium of organizational and dynamic features that maintain physiology. The …

[HTML][HTML] Exercise-induced oxidative stress: Friend or foe?

SK Powers, R Deminice, M Ozdemir… - Journal of sport and …, 2020 - Elsevier
The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

Evolution of the knowledge of free radicals and other oxidants

S Di Meo, P Venditti - Oxidative medicine and cellular longevity, 2020 - Wiley Online Library
Free radicals are chemical species (atoms, molecules, or ions) containing one or more
unpaired electrons in their external orbitals and generally display a remarkable reactivity …

Sources of vascular nitric oxide and reactive oxygen species and their regulation

J Tejero, S Shiva, MT Gladwin - Physiological reviews, 2019 - journals.physiology.org
Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Antioxidants and exercise performance: with a focus on vitamin E and C supplementation

MR Higgins, A Izadi, M Kaviani - International Journal of Environmental …, 2020 - mdpi.com
Antioxidant supplementation, including vitamin E and C supplementation, has recently
received recognition among athletes as a possible method for enhancing athletic …

Mechanisms and mitochondrial redox signaling in photobiomodulation

MR Hamblin - Photochemistry and photobiology, 2018 - Wiley Online Library
Photobiomodulation (PBM) involves the use of red or near‐infrared light at low power
densities to produce a beneficial effect on cells or tissues. PBM therapy is used to reduce …