Abstract Treatment of migraine is on the cusp of a new era with the development of drugs
that target the trigeminal sensory neuropeptide calcitonin gene-related peptide (CGRP) or its …

Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …

The cellular and molecular mechanisms mediating histamine-independent itch in primary
sensory neurons are largely unknown. Itch induced by chloroquine (CQ) is a common side …

Calcitonin gene-related peptide (CGRP) has been detected in increased amounts in
external jugular venous blood during migraine attacks. However, it is unknown whether this …

Background Calcitonin gene–related peptide (CGRP) may have a causative role in
migraine. We therefore hypothesized that a CGRP-receptor antagonist might be effective in …

Introduction: Calcitonin gene-related peptide (CGRP) is a key molecule in migraine
pathogenesis. Intravenous CGRP infusion triggers delayed migraine-like attacks in patients …

This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …

Migraine is one of the most disabling and prevalent of all disorders. To improve
understanding of migraine mechanisms and to suggest a new therapeutic target, we …

Calcitonin gene‐related peptide (CGRP) is a key mediator in primary headaches including
migraine. Animal models of meningeal nociception demonstrate both peripheral and central …

The interaction between components of the nervous system and multiple target cells in the
cutaneous immune system has been receiving increasing attention. It has been observed …