[HTML][HTML] The human transcription factors
Transcription factors (TFs) recognize specific DNA sequences to control chromatin and
transcription, forming a complex system that guides expression of the genome. Despite keen …
transcription, forming a complex system that guides expression of the genome. Despite keen …
Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases
The identification of interactions between drugs/compounds and their targets is crucial for
the development of new drugs. In vitro screening experiments (ie bioassays) are frequently …
the development of new drugs. In vitro screening experiments (ie bioassays) are frequently …
The InterPro protein families and domains database: 20 years on
M Blum, HY Chang, S Chuguransky… - Nucleic acids …, 2021 - academic.oup.com
Abstract The InterPro database (https://www. ebi. ac. uk/interpro/) provides an integrative
classification of protein sequences into families, and identifies functionally important …
classification of protein sequences into families, and identifies functionally important …
Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet
Pearl millet is an important cereal crop worldwide and shows superior heat tolerance. Here,
we developed a graph-based pan-genome by assembling ten chromosomal genomes with …
we developed a graph-based pan-genome by assembling ten chromosomal genomes with …
The PSIPRED protein analysis workbench: 20 years on
DWA Buchan, DT Jones - Nucleic acids research, 2019 - academic.oup.com
The PSIPRED Workbench is a web server offering a range of predictive methods to the
bioscience community for 20 years. Here, we present the work we have completed to update …
bioscience community for 20 years. Here, we present the work we have completed to update …
Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v. 14.0)
H Mi, A Muruganujan, X Huang, D Ebert, C Mills… - Nature protocols, 2019 - nature.com
The PANTHER classification system (http://www. pantherdb. org) is a comprehensive system
that combines genomes, gene function classifications, pathways and statistical analysis …
that combines genomes, gene function classifications, pathways and statistical analysis …
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools
H Mi, A Muruganujan, D Ebert, X Huang… - Nucleic acids …, 2019 - academic.oup.com
Abstract PANTHER (Protein Analysis Through Evolutionary Relationships, http://pantherdb.
org) is a resource for the evolutionary and functional classification of genes from organisms …
org) is a resource for the evolutionary and functional classification of genes from organisms …
The Pfam protein families database in 2019
The last few years have witnessed significant changes in Pfam (https://pfam. xfam. org). The
number of families has grown substantially to a total of 17,929 in release 32.0. New …
number of families has grown substantially to a total of 17,929 in release 32.0. New …
InterPro in 2019: improving coverage, classification and access to protein sequence annotations
AL Mitchell, TK Attwood, PC Babbitt… - Nucleic acids …, 2019 - academic.oup.com
Abstract The InterPro database (http://www. ebi. ac. uk/interpro/) classifies protein
sequences into families and predicts the presence of functionally important domains and …
sequences into families and predicts the presence of functionally important domains and …
HMMER web server: 2018 update
SC Potter, A Luciani, SR Eddy, Y Park… - Nucleic acids …, 2018 - academic.oup.com
Abstract The HMMER webserver [http://www. ebi. ac. uk/Tools/hmmer] is a free-to-use
service which provides fast searches against widely used sequence databases and profile …
service which provides fast searches against widely used sequence databases and profile …