The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …

Background: Activated macrophages contribute to the pathogenesis of vascular disease.
Vein graft failure is a major clinical problem with limited therapeutic options. PCSK9 …

Simple Summary Inflammatory processes are involved in the development and progression
of coronary artery disease. Environmental factors, including hyperglycaemia …

Small-diameter artificial vascular grafts (SDAVG) are used to bypass blood flow in arterial
occlusive diseases such as coronary heart or peripheral arterial disease. However, SDAVGs …

NF-κB is generally recognized as an important regulator of ageing, through its roles in
cellular senescence and inflammatory pathways. Activated in virtually all cell-cell …

Thrombogenesis remains the primary failure of synthetic vascular grafts. Endothelial
coverage is crucial to provide an antithrombogenic surface. However, most synthetic …

Coronary artery disease (CAD) remains one of the most important causes of morbidity and
mortality worldwide, and the availability of percutaneous or surgical revascularization …

In recent years, there has been growing evidence that vascular pathologies arise in sites
experiencing an altered haemodynamic environment. Fluid shear stress (FSS) is an …

The rate of the remodeling of the arterialized saphenous vein conduit limits the outcomes of
coronary artery bypass graft surgery (CABG), which may be influenced by endothelial …