Organosulfur compounds have long played a vital role in organic chemistry and in the
development of novel chemical structures and architectures. Prominent among these …

1. INTRODUCTION This review article is concerned with the use of compounds 1 and 2
(Figure 1) as effective and very versatile reagents for trifluoromethylation reactions of a …

Transition-metal-catalyzed C–H bond functionalizations have had an enormous influence on
organic synthesis in recent times. However, the use of low-abundance 4d and 5d metals is …

Organofluorine compounds have attracted extensive attention in various industrial fields due
to their unique chemical and physical properties. Despite increasing demand in a wide …

Fluorine, often called as “a small atom with a big ego”, 1 lies in the second row and the 17th
column in the periodic table of the chemical elements. This unique position in the periodic …

Abstract (Deuterium‐labeled) CF2H‐and CFH2‐moieties are of high interest in drug
discovery. The high demand for the incorporation of these fluoroalkyl moieties into molecular …

1. INTRODUCTION Fluorine is the most abundant halogen in the Earth, s crust. 1 However,
only a dozen fluorinated organic compounds have been identified in nature. 2 Most of the …

Fluorinated organic compounds increasingly gain importance in numerous areas of
chemistry and everyday life. Building blocks which contain fluorinated entities are of high …

Method B 692 3.7. Selective Trifluoromethylation of Multi-Functional Substrates 693 3.8.
Enantioselective Trifluoromethylation 695 3.8. 1. Aldehydes and Ketones: With Cinchona …

Conspectus Fluorine, which is the most electronegative element and has a small atomic
radius, plays a key role in pharmaceutical, agrochemical, and materials sciences. One of the …