Molecular adjuvants can be used to enhance the natural destructive mechanisms of freezing
within tissue. This review discusses their use in the growing field of combinatorial or …

In clinics, the minimally invasive freezing therapy, commonly known as cryosurgery, has
been increasingly used for the controlled destruction of tumor tissue. However, there are still …

Aim: In this study, we describe the biodistribution of CYT-6091, a colloidal gold (Au)-based
nanomedicine that targets the delivery of TNF-α to solid tumors. Materials & methods: A …

Background The low response rate of immune checkpoint inhibitors (ICIs) prompts the
exploration of novel combination therapies for patients with hepatocellular carcinoma …

Recently, a new tumor ablation modality based on freezing immediately followed by a rapid
and strong enough heating has been proved to be more effective and flexible than …

The degree of the cell injury caused by low temperatures depends on the freezing protocol
(the cooling rate, the thawing rate, the exposition duration, the minimal temperature) as well …

Cryosurgery is a minimally invasive cancer treatment using cryogenic temperatures.
Intraoperative monitoring of iceball growth is an advantage of the treatment. However …

A new system aiming for more effective thermal treatment of tumor is presented in this paper.
It facilitates liquid nitrogen (LN2) cooling and radiofrequency (RF) heating in tissue. The bio …

It is well-known that a successful cell destruction is a time-temperature-dependent process,
so that the less temperature and the more freezing time, the more cell death will occur …

Background This study compared a co‐ablation (CA) system, which is a novel ablation
device, with an argon‐helium cryoablation (AHC) system. We aimed to compare the efficacy …