Point-of-care nucleic acid testing for infectious diseases

A Niemz, TM Ferguson, DS Boyle - Trends in biotechnology, 2011 - cell.com
Nucleic acid testing for infectious diseases at the point of care is beginning to enter clinical
practice in developed and developing countries; especially for applications requiring fast …

[HTML][HTML] Early infant HIV-1 diagnosis programs in resource-limited settings: opportunities for improved outcomes and more cost-effective interventions

AL Ciaranello, JE Park, L Ramirez-Avila, KA Freedberg… - BMC medicine, 2011 - Springer
Early infant diagnosis (EID) of HIV-1 infection confers substantial benefits to HIV-infected
and HIV-uninfected infants, to their families, and to programs providing prevention of mother …

Rapid detection of HIV-1 proviral DNA for early infant diagnosis using recombinase polymerase amplification

DS Boyle, DA Lehman, L Lillis, D Peterson, M Singhal… - MBio, 2013 - Am Soc Microbiol
Early diagnosis and treatment of human immunodeficiency virus type 1 (HIV-1) infection in
infants can greatly reduce mortality rates. However, current infant HIV-1 diagnostics cannot …

[HTML][HTML] Dynamics and constraints of early infant diagnosis of HIV infection in rural Kenya

AS Hassan, EM Sakwa, HM Nabwera… - AIDS and Behavior, 2012 - Springer
A cohort design was used to determine uptake and drop out of 213 HIV-exposed infants
eligible for Early Infant Diagnosis (EID) of HIV. To explore service providers and care givers …

If you text them, they will come: using the HIV infant tracking system to improve early infant diagnosis quality and retention in Kenya

S Finocchario-Kessler, BJ Gautney, S Khamadi… - Aids, 2014 - journals.lww.com
Objective: The objective of this study is to evaluate the impact of the HIV Infant Tracking
System (HITSystem) for quality improvement of early infant diagnosis (EID) of HIV services …

[HTML][HTML] Electricity-free amplification and detection for molecular point-of-care diagnosis of HIV-1

J Singleton, JL Osborn, L Lillis, K Hawkins, D Guelig… - PloS one, 2014 - journals.plos.org
In resource-limited settings, the lack of decentralized molecular diagnostic testing and
sparse access to centralized medical facilities can present a critical barrier to timely …

[HTML][HTML] Missed opportunities for early infant HIV diagnosis: results of a national study in South Africa

SA Woldesenbet, D Jackson, AE Goga… - JAIDS Journal of …, 2015 - journals.lww.com
Background: Services to diagnose early infant HIV infection should be offered at the 6-week
immunization visit. Despite high 6-week immunization attendance, the coverage of early …

[HTML][HTML] Introducing a multi-site program for early diagnosis of HIV infection among HIV-exposed infants in Tanzania

H Nuwagaba-Biribonwoha, B Werq-Semo, A Abdallah… - BMC pediatrics, 2010 - Springer
Abstract Background In Tanzania, less than a third of HIV infected children estimated to be in
need of antiretroviral therapy (ART) are receiving it. In this setting where other infections and …

p24 antigen rapid test for diagnosis of acute pediatric HIV infection

ZA Parpia, R Elghanian, A Nabatiyan… - JAIDS Journal of …, 2010 - journals.lww.com
Currently, the majority of HIV-infected infants are found within limited-resource settings,
where inadequate screening for HIV due to the lack of access to simple and affordable point …

Optimal decentralization of early infant diagnosis of HIV in resource-limited settings

S Deo, M Sohoni - Manufacturing & Service Operations …, 2015 - pubsonline.informs.org
Early infant diagnosis (EID) programs in many resource-limited settings are aimed at
diagnosing infants born to HIV-infected mothers. Because of the complexity of the diagnostic …