[HTML][HTML] Current developments of SELEX technologies and prospects in the aptamer selection with clinical applications

DJ Chinchilla-Cárdenas, JS Cruz-Méndez… - Journal of Genetic …, 2024 - Elsevier
Aptamers are single-stranded oligonucleotide sequences capable of binding to specific
ligands with high affinity. In this manner, they are like antibodies but have advantages such …

Proteinase K pretreatment for the quantitative recovery and sensitive detection of the tuberculosis biomarker mannose-capped lipoarabinomannan spiked into human …

E Clarke, R Robinson, LB Laurentius… - Analytical …, 2023 - ACS Publications
This paper reports on an investigation of an enzymatic pretreatment protocol using
proteinase K (ProK) for the analysis of human serum samples spiked with mannose-capped …

Modulators targeting protein-protein interactions in Mycobacterium tuberculosis

G Luo, T Ming, L Yang, L He, T Tao, Y Wang - Microbiological Research, 2024 - Elsevier
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (M.
tuberculosis), mainly transmitted through droplets to infect the lungs, and seriously affecting …

Caracterización bioinformática de aptámeros de ADN seleccionados contra la proteína quinasa (PknG) de Mycobacterium tuberculosis

BR Pesantes Morzan, MP De Zavala Romaña - repositorioacademico.upc.edu.pe
La enzima PknG es una de las 11 serina-treonina quinasas presentes en Mycobacterium
tuberculosis. Estas enzimas regulan diferentes procesos fisiológicos. Se ha reportado que …