Bacterial membrane lipids in the action of antimicrobial agents

RM Epand, RF Epand - Journal of Peptide Science, 2011 - Wiley Online Library
Many antimicrobial agents that target bacteria are cationic and can interact with the anionic
lipid components that are exposed on the bacterial membrane. Bacteria vary widely in the …

Antituberculosis drug research: a critical overview

Beena, DS Rawat - Medicinal research reviews, 2013 - Wiley Online Library
The increasing drug resistance of M ycobacterium tuberculosis to the currently used drugs
and HIV coinfection has caused alarm in the international scientific community …

Sonorensin: a new bacteriocin with potential of an anti-biofilm agent and a food biopreservative

L Chopra, G Singh, K Kumar Jena, DK Sahoo - Scientific reports, 2015 - nature.com
The emergence of antibiotic resistant bacteria has led to exploration of alternative
therapeutic agents such as ribosomally synthesized bacterial peptides known as …

Antimicrobial mechanism of flavonoids against Escherichia coli ATCC 25922 by model membrane study

M He, T Wu, S Pan, X Xu - Applied Surface Science, 2014 - Elsevier
Antimicrobial mechanism of four flavonoids (kaempferol, hesperitin,(+)-catechin hydrate,
biochanin A) against Escherichia coli ATCC 25922 was investigated through cell …

Antibacterial peptide nucleic acids—facts and perspectives

M Wojciechowska, M Równicki, A Mieczkowski… - Molecules, 2020 - mdpi.com
Antibiotic resistance is an escalating, worldwide problem. Due to excessive use of
antibiotics, multidrug-resistant bacteria have become a serious threat and a major global …

Indolicidin revisited: biological activity, potential applications and perspectives of an antimicrobial peptide not yet fully explored

J Batista Araujo, G Sastre de Souza… - World Journal of …, 2022 - Springer
The emergence of multidrug-resistant bacteria, viruses and tumors is a serious threat to
public health. Among natural peptides, indolicidin, a 13-residue peptide belonging to the …

Boosting synergistic effects of short antimicrobial peptides with conventional antibiotics against resistant bacteria

CL Wu, KL Peng, BS Yip, YH Chih… - Frontiers in …, 2021 - frontiersin.org
The global spread of antibiotic-resistant infections has meant that there is an urgent need to
develop new antimicrobial alternatives. In this study, we developed a strategy to boost …

Two hits are better than one: membrane-active and DNA binding-related double-action mechanism of NK-18, a novel antimicrobial peptide derived from mammalian …

J Yan, K Wang, W Dang, R Chen, J Xie… - Antimicrobial agents …, 2013 - Am Soc Microbiol
The extensive use and misuse of antibiotics in medicine result in the emergence of multidrug-
resistant bacteria, creating an urgent need for the development of new chemotherapeutic …

Vitamin B12 as a carrier of peptide nucleic acid (PNA) into bacterial cells

M Równicki, M Wojciechowska, AJ Wierzba… - Scientific reports, 2017 - nature.com
Short modified oligonucleotides targeted at bacterial DNA or RNA could serve as
antibacterial agents provided that they are efficiently taken up by bacterial cells. However …

Antimicrobial Peptides Display Strong Synergy with Vancomycin Against Vancomycin-Resistant E. faecium, S. aureus, and Wild-Type E. coli

CL Wu, JY Hsueh, BS Yip, YH Chih, KL Peng… - International Journal of …, 2020 - mdpi.com
There is an urgent and imminent need to develop new antimicrobials to fight against
antibiotic-resistant bacterial and fungal strains. In this study, a checkerboard method was …