Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium

M Packer - Journal of the American College of Cardiology, 2018 - jacc.org
Epicardial adipose tissue has unique properties that distinguish it from other depots of
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …

Echocardiographic epicardial fat: a review of research and clinical applications

G Iacobellis, HJ Willens - Journal of the American Society of …, 2009 - Elsevier
Epicardial fat plays a role in cardiovascular diseases. Because of its anatomic and functional
proximity to the myocardium and its intense metabolic activity, some interactions between …

Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease

VB Patel, S Shah, S Verma, GY Oudit - Heart failure reviews, 2017 - Springer
Obesity and diabetes are strongly associated with metabolic and cardiovascular disorders
including dyslipidemia, coronary artery disease, hypertension, and heart failure. Adipose …

Leptin-aldosterone-neprilysin axis: identification of its distinctive role in the pathogenesis of the three phenotypes of heart failure in people with obesity

M Packer - Circulation, 2018 - Am Heart Assoc
Obesity (especially visceral adiposity) can be associated with 3 different phenotypes of heart
failure: heart failure with a reduced ejection fraction, heart failure with a preserved ejection …

Different adipose depots: their role in the development of metabolic syndrome and mitochondrial response to hypolipidemic agents

B Bjørndal, L Burri, V Staalesen, J Skorve… - Journal of …, 2011 - Wiley Online Library
Adipose tissue metabolism is closely linked to insulin resistance, and differential fat
distributions are associated with disorders like hypertension, diabetes, and cardiovascular …

Role of inflammation in the pathogenesis of atrial fibrillation

K Ihara, T Sasano - Frontiers in Physiology, 2022 - frontiersin.org
Atrial fibrillation (AF) is one of the most common arrhythmias encountered in clinical practice.
AF is a major risk factor for stroke, which is associated with high mortality and great disability …

Bariatric surgery and cardiovascular risk factors: a scientific statement from the American Heart Association

P Poirier, MA Cornier, T Mazzone, S Stiles… - Circulation, 2011 - Am Heart Assoc
The rate of obesity is rising logarithmically, especially in those with severe obesity (body
mass index [BMI] 40 kg/m2). Cardiologists, endocrinologists, internists, family practitioners …

Adipokines in periaortic and epicardial adipose tissue: differential expression and relation to atherosclerosis

SG Spiroglou, CG Kostopoulos, JN Varakis… - … of atherosclerosis and …, 2010 - jstage.jst.go.jp
Aim: Adipokines are protein products of adipose tissue with paracrine and endocrine
actions, which have been implicated in the pathogenesis of cardiovascular disease. Locally …

Luseogliflozin reduces epicardial fat accumulation in patients with type 2 diabetes: a pilot study

R Bouchi, M Terashima, Y Sasahara… - Cardiovascular …, 2017 - Springer
Background Accumulation of epicardial fat (EF) is associated with increased cardio-
metabolic risks and coronary events, independently of traditional cardiovascular risk factors …

[HTML][HTML] Garlic and heart disease

R Varshney, MJ Budoff - The Journal of nutrition, 2016 - Elsevier
Background: Thousands of studies have been published based on animal and human
studies evaluating garlic's effects and safety. Objective: We reviewed the available literature …