[HTML][HTML] Pathogenesis, epidemiology and control of Group A Streptococcus infection

S Brouwer, T Rivera-Hernandez, BF Curren… - Nature Reviews …, 2023 - nature.com
Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …

Research priorities for the primordial prevention of acute rheumatic fever and rheumatic heart disease by modifying the social determinants of health

MG Baker, MY Masterson, M Shung-King, A Beaton… - BMJ global …, 2023 - gh.bmj.com
The social determinants of health (SDH), such as access to income, education, housing and
healthcare, strongly shape the occurrence of acute rheumatic fever (ARF) and rheumatic …

[HTML][HTML] Risk factors for group A streptococcal pharyngitis and skin infections: a case control study

J Bennett, NJ Moreland, J Zhang, J Crane… - The Lancet Regional …, 2022 - thelancet.com
Summary Background Group A streptococcal (GAS) infections can trigger an immune-
mediated response resulting in acute rheumatic fever (ARF). The role of social and …

[HTML][HTML] Risk factors for acute rheumatic fever: a case-control study

MG Baker, J Gurney, NJ Moreland… - The Lancet Regional …, 2022 - thelancet.com
Background Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain an
inequitable cause of avoidable suffering and early death in many countries, including …

[HTML][HTML] A worldwide population of Streptococcus pyogenes strains circulating among school-aged children in Auckland, New Zealand: a genomic epidemiology …

JA Lacey, J Bennett, TB James, BS Hines… - The Lancet Regional …, 2024 - thelancet.com
Background Acute rheumatic fever (ARF) is a serious post-infectious sequala of Group A
Streptococcus (GAS, Streptococcus pyogenes). In New Zealand (NZ) ARF is a major cause …

Cytokine imbalance in acute rheumatic fever and rheumatic heart disease: Mechanisms and therapeutic implications

FM Middleton, R McGregor, RH Webb, NJ Wilson… - Autoimmunity …, 2022 - Elsevier
Abstract Acute Rheumatic Fever (ARF) and Rheumatic Heart Disease (RHD) are
autoimmune sequelae of Group A Streptococcus infection with significant global disease …

[HTML][HTML] The rise and fall of acute rheumatic fever and rheumatic heart disease: a mini review

Y Liang, D Yu, Q Lu, Y Zheng, Y Yang - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Introduction The incidences of acute rheumatic fever (ARF) and rheumatic heart disease
(RHD), which were leading causes of death in children in the 1920s, have decreased …

Subcutaneous infusion of high-dose benzathine penicillin G is safe, tolerable, and suitable for less-frequent dosing for rheumatic heart disease secondary prophylaxis …

J Kado, S Salman, TK Hla, S Enkel… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Since 1955, the recommended strategy for rheumatic heart disease (RHD) secondary
prophylaxis has been benzathine penicillin G [BPG; 1.2 MU (900 mg)] injections …

Increased Breadth of Group A Streptococcus Antibody Responses in Children With Acute Rheumatic Fever Compared to Precursor Pharyngitis and Skin Infections

AL Whitcombe, R McGregor, J Bennett… - The Journal of …, 2022 - academic.oup.com
Abstract Background Group A Streptococcus (GAS) causes superficial pharyngitis and skin
infections as well as serious autoimmune sequelae such as acute rheumatic fever (ARF) …

Research opportunities for the primary prevention and management of acute rheumatic fever and rheumatic heart disease: a national heart, lung, and blood Institute …

J Rwebembera, JW Cannon, A Sanyahumbi… - BMJ Global …, 2023 - gh.bmj.com
Primary prevention of acute rheumatic fever (ARF) and rheumatic heart disease (RHD)
encompasses the timely diagnosis and adequate treatment of the superficial group A …