Structural and functional defects within the lungs of children with cystic fibrosis (CF) are
detectable soon after birth and progress throughout preschool years often without overt …

Objective Imaging represents an important noninvasive means to assess cystic fibrosis (CF)
lung disease, which remains the main cause of morbidity and mortality in CF patients. While …

To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest
MRI has been historically out of the scope of routine clinical imaging due to technical …

Cystic fibrosis is a genetic disease with multisystem involvement and associated morbidity
and mortality that are most directly related to progressive lung disease. The hallmark …

Imaging plays a pivotal role in the noninvasive assessment of cystic fibrosis (CF)-related
lung damage, which remains the main cause of morbidity and mortality in children with CF …

With an increasing number of patients with cystic fibrosis (CF) receiving highly effective
CFTR (cystic fibrosis transmembrane regulator protein) modulator therapy, particularly at a …

The recent introduction of triple-combination CF transmembrane regulator therapy has put
further emphasis on the need for sensitive methods of monitoring treatment response to …

The outlook for those with cystic fibrosis (CF) has never been brighter with ever increasing
life expectancy and the approval of the highly effective CFTR modulators, such as …

Background Medical radiation exposure is of increasing concern in patients with cystic
fibrosis (PWCF) due to improving life expectancy. We aimed to assess and quantify the …

Abstract Background Functional Respiratory Imaging (FRI) combines HRCT scans with
computational fluid dynamics to provide objective and quantitative information about lung …