Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
[HTML][HTML] Exploring the expanding universe of small RNAs
The world of small noncoding RNAs (sncRNAs) is ever-expanding, from small interfering
RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs …
RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs …
Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets
Background tRFs, 14 to 32 nt long single-stranded RNA derived from mature or precursor
tRNAs, are a recently discovered class of small RNA that have been found to be present in …
tRNAs, are a recently discovered class of small RNA that have been found to be present in …
Functional interactions among microRNAs and long noncoding RNAs
JH Yoon, K Abdelmohsen, M Gorospe - Seminars in cell & developmental …, 2014 - Elsevier
In mammals, the vast majority of transcripts expressed are noncoding RNAs, ranging from
short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the …
short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the …
Long non-coding RNA linc00673 regulated non-small cell lung cancer proliferation, migration, invasion and epithelial mesenchymal transition by sponging miR-150 …
W Lu, H Zhang, Y Niu, Y Wu, W Sun, H Li, J Kong… - Molecular cancer, 2017 - Springer
Background The function of a new long non-coding RNA linc00673 remains unclear. While
identified as an oncogenic player in non-small cell lung cancer (NSCLC), linc00673 was …
identified as an oncogenic player in non-small cell lung cancer (NSCLC), linc00673 was …
Biogenesis and function of transfer RNA-related fragments (tRFs)
Noncoding small RNAs arise from the various un-annotated and annotated regions of the
genome. When they arise from annotated genes, the noncoding small RNAs are functionally …
genome. When they arise from annotated genes, the noncoding small RNAs are functionally …
[HTML][HTML] tRNA fragments in human health and disease
P Anderson, P Ivanov - FEBS letters, 2014 - Elsevier
Transfer RNA (tRNA) is traditionally considered to be an adaptor molecule that helps
ribosomes to decode messenger RNA (mRNA) and synthesize protein. Recent studies have …
ribosomes to decode messenger RNA (mRNA) and synthesize protein. Recent studies have …
LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1
Y Shan, J Ma, Y Pan, J Hu, B Liu, L Jia - Cell death & disease, 2018 - nature.com
Accumulating evidence suggests long noncoding RNAs (lncRNAs) play an important role in
cancer progression. However, the function of lncRNA SNHG7 in colorectal cancer (CRC) …
cancer progression. However, the function of lncRNA SNHG7 in colorectal cancer (CRC) …
[HTML][HTML] Cytoplasmic RNA decay pathways-Enzymes and mechanisms
A Łabno, R Tomecki, A Dziembowski - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
RNA decay plays a crucial role in post-transcriptional regulation of gene expression. Work
conducted over the last decades has defined the major mRNA decay pathways, as well as …
conducted over the last decades has defined the major mRNA decay pathways, as well as …
Long non-coding RNA (lncRNA) roles in cell biology, neurodevelopment and neurological disorders
V Aliperti, J Skonieczna, A Cerase - Non-coding RNA, 2021 - mdpi.com
Development is a complex process regulated both by genetic and epigenetic and
environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …
environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …