MicroRNAs in cancer and cardiovascular disease

M Ilieva, R Panella, S Uchida - Cells, 2022 - mdpi.com
Although cardiac tumor formation is rare, accumulating evidence suggests that the two
leading causes of deaths, cancers, and cardiovascular diseases are similar in terms of …

Recent progress in the development of aptasensors for cancer diagnosis: focusing on aptamers against cancer biomarkers

S Vandghanooni, Z Sanaat, R Farahzadi… - Microchemical …, 2021 - Elsevier
The early diagnosis of cancer is a very critical step in the treatment and management of the
disease. However, some cancers might manifest with nonspecific symptoms resulting in the …

MiR-155 inhibitor-laden exosomes reverse resistance to cisplatin in a 3D tumor spheroid and xenograft model of oral cancer

AA Sayyed, P Gondaliya, M Mali, A Pawar… - Molecular …, 2021 - ACS Publications
Cisplatin resistance is one of the major concerns in the treatment of oral squamous cell
carcinoma (OSCC). Accumulating evidence suggests microRNA (miRNA) dysregulation as …

miR-142: A Master Regulator in Hematological Malignancies and Therapeutic Opportunities

W Huang, D Paul, GA Calin, R Bayraktar - Cells, 2023 - mdpi.com
MicroRNAs (miRNAs) are a type of non-coding RNA whose dysregulation is frequently
associated with the onset and progression of human cancers. miR-142, an ultra-conserved …

Circular RNA hsa_circ_0001829 promotes gastric cancer progression through miR-155-5p/SMAD2 axis

Q Niu, Z Dong, M Liang, Y Luo, H Lin, M Lin… - Journal of Experimental …, 2020 - Springer
Background Accumulating evidences have shown that circular RNAs (circRNAs) play
important roles in regulating the pathogenesis of cancer. However, the role of circRNAs in …

The epitranscriptome in miRNAs: crosstalk, detection, and function in cancer

D del Valle-Morales, P Le, M Saviana, G Romano… - Genes, 2022 - mdpi.com
The epitranscriptome encompasses all post-transcriptional modifications that occur on
RNAs. These modifications can alter the function and regulation of their RNA targets, which …

Demethylated miR-216a regulates high mobility group box 3 promoting growth of esophageal cancer cells through Wnt/β-catenin pathway

CX Sun, F Zhu, L Qi - Frontiers in Oncology, 2021 - frontiersin.org
Background Esophageal cancer (EC) is the eighth most common cause of cancer-
associated mortality in humans. Recent studies have revealed the important roles of …

Assessment of circulating miR-20b, miR-221, and miR-155 in occupationally lead-exposed workers of North-Western India

P Mitra, T Goyal, P Singh, S Sharma… - Environmental Science and …, 2021 - Springer
Lead (Pb), a toxic heavy metal, is capable of inducing several adverse health effects
following its accumulation in the body. Lead is a potential carcinogen, capable of causing …

Lead (Pb) exposure is associated with changes in the expression levels of circulating miRNAS (miR-155, miR-126) in Mexican women

ÁC Ochoa-Martínez, JA Varela-Silva… - Environmental …, 2021 - Elsevier
The environmental contamination with lead (Pb) is considered a critical issue worldwide.
Therefore, this study aimed to evaluate the expression levels of circulating miRNAs (miR …

The role of mitochondrial miRNAs in the development of radon-induced lung cancer

A Kussainova, O Bulgakova, A Aripova, Z Khalid… - Biomedicines, 2022 - mdpi.com
MicroRNAs are short, non-coding RNA molecules regulating gene expression by inhibiting
the translation of messenger RNA (mRNA) or leading to degradation. The miRNAs are …