OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …

Through years of evolution, biological soft fibrous tissues have developed remarkable
functional properties, unique hierarchical architectures, and-most notably, an unparalleled …

Although hundreds of samples obtained from ascending thoracic aortic aneurysms (ATAA)
of patients undergoing elective surgical repair have already been characterized …

Purpose.: We tested the hypothesis that there are age-and race-related differences in
posterior scleral material properties, using eyes from human donors of European (20–90 …

To characterize the material properties of posterior and peripapillary sclera from human
donors, and to investigate the macro-and micro-scale strains as potential control …

Intracranial aneurysms are pathological enlargements of brain arteries that are believed to
arise from progressive wall degeneration and remodeling. Earlier work using classical …

Porous synthetic grafts made of poly (glycerol sebacate)(PGS) can transform into autologous
vascular conduits in vivo upon degradation of PGS. A long-held doctrine in tissue …

Characterizing the collagen fiber orientation and organization in the eye is necessary for a
complete understanding of ocular biomechanics. In this study, we assess the performance of …

Vasculopathy and the consequential ischemia are major medical challenges. Grafting is an
effective treatment to vascular occlusion. However, autologous grafting, despite scarcity, is …

Background Lower urinary tract syndrome (LUTS) is a group of urinary tract symptoms and
signs that can include urinary incontinence. Advancing age is a major risk factor for LUTS; …