The August Krogh principle, stating that for any particular question in biology, nature holds
an ideal study system, was applied by choosing the anorexic, long-distance migration of …

Glutamine synthetase (GS) has long been known to be expressed exclusively in pericentral
hepatocytes most proximal to the central veins of liver lobuli. This enzyme as well as its …

The liver shows net glutamine uptake after a protein-containing meal, during uncontrolled
diabetes, sepsis and short-term starvation, but changes to net release during long-term …

The goal of this study was to systematically evaluate the molecular activities of endocrine-,
amino acid and peptide transporters-, and metabolic enzyme-related genes in 35-day-old …

Weight loss and malnutrition have long been associated with a poor clinical outcome after
surgery (1). Anorexia, muscle wasting and progressive depletion of adipose tissue have …

Mice bearing the Lewis lung carcinoma showed a high tumour glutaminase activity and
significantly higher concentrations of most amino acids than in both the liver and the skeletal …

The activities of the two key enzymes involved in glutamine metabolism, glutaminase (EC
3.5. 1.2) and glutamine synthetase (EC 6.3. 1.2), have been measured in the various tissues …

Glutamine is synthesized in skeletal muscle, released to the circulation, and transported to
other tissues, where it may provide important substrate for gluconeogenesis …

Previously, we observed increased plasma arginine (ARG) concentrations after glutamine
(GLN)-enriched diets, in combination with clinical benefits. GLN delivers nitrogen for ARG …

Skeletal muscle exports glutamine (Gln) and increases the expression of the enzyme
glutamine synthetase (GS) in response to physiological stress. Acute stress or direct …