Numerous human diseases arise from alterations of genetic information, most notably DNA
mutations. Thought to be merely the intermediate between DNA and protein, changes in …

Diploidy has profound implications for population genetics and susceptibility to genetic
diseases. Although two copies are present for most genes in the human genome, they are …

An intricate network of cis-and trans-elements acts on RNA N 6-methyladenosine (m6A),
which in turn may affect gene expression and, ultimately, human health. A complete …

In situ capturing technologies add tissue context to gene expression data, with the potential
of providing a greater understanding of complex biological systems. However, splicing …

Precise calling of promiscuous adenosine-to-inosine RNA editing sites from transcriptomic
datasets is hindered by DNA mutations and sequencing/mapping errors. Here, we present a …

Although long-read RNA-seq is increasingly applied to characterize full-length transcripts it
can also enable detection of nucleotide variants, such as genetic mutations or RNA editing …

Pervasive allelic variation at both gene and single nucleotide level (SNV) between
individuals is commonly associated with complex traits in humans and animals. Allele …

Simple Summary In order to investigate RNA editing sites affecting IMF (which is associated
with pork quality and human insulin resistance.), we analyzed the transcriptome and …

The deep ocean harbors a group of highly diversified microbes, while our understanding of
the active microbes that are real contributors to the nutrient cycle remains limited. In this …

Recent studies have shown that structuralized long non-coding RNAs (lncRNAs) play
important roles in genetic and epigenetic processes. The spatial structures of most lncRNAs …