Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity
The comparatively milder infections with the Omicron variant and higher levels of population
immunity have raised hopes for a weakening of the pandemic. We argue that the lower …
immunity have raised hopes for a weakening of the pandemic. We argue that the lower …
Towards SARS-CoV-2 serotypes?
E Simon-Loriere, O Schwartz - Nature Reviews Microbiology, 2022 - nature.com
The magnitude of immune evasion of Omicron raises the question whether it should be
considered as a distinct SARS-CoV-2 serotype. Here, we discuss lines of evidence in …
considered as a distinct SARS-CoV-2 serotype. Here, we discuss lines of evidence in …
[HTML][HTML] Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants
The BQ and XBB subvariants of SARS-CoV-2 Omicron are now rapidly expanding, possibly
due to altered antibody evasion properties deriving from their additional spike mutations …
due to altered antibody evasion properties deriving from their additional spike mutations …
Antigenic cartography of SARS-CoV-2 reveals that Omicron BA. 1 and BA. 2 are antigenically distinct
AZ Mykytyn, M Rissmann, A Kok, ME Rosu… - Science …, 2022 - science.org
The emergence and rapid spread of SARS-CoV-2 variants may affect vaccine efficacy
substantially. The Omicron variant termed BA. 2, which differs substantially from BA. 1 based …
substantially. The Omicron variant termed BA. 2, which differs substantially from BA. 1 based …
[HTML][HTML] Humoral immune escape by current SARS-CoV-2 variants BA. 2.86 and JN. 1, December 2023
LM Jeworowski, B Mühlemann, F Walper… - …, 2024 - eurosurveillance.org
Variant BA. 2.86 and its descendant, JN. 1, of SARS-CoV-2 are rising in incidence across
Europe and globally. We isolated recent JN. 1, BA. 2.86, EG. 5, XBB. 1.5 and earlier variants …
Europe and globally. We isolated recent JN. 1, BA. 2.86, EG. 5, XBB. 1.5 and earlier variants …
Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA. 1 and BA. 2 by convalescent and vaccine serum and monoclonal antibodies
Summary Background In recent months, Omicron variants of SARS-CoV-2 have become
dominant in many regions of the world, and case numbers with Omicron subvariants BA. 1 …
dominant in many regions of the world, and case numbers with Omicron subvariants BA. 1 …
Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial
Vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection wanes over time, requiring updated boosters. In a phase 2, open-label, randomized …
infection wanes over time, requiring updated boosters. In a phase 2, open-label, randomized …
Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron
K van der Straten, D Guerra, MJ van Gils, I Bontjer… - Immunity, 2022 - cell.com
Large-scale vaccination campaigns have prevented countless hospitalizations and deaths
due to COVID-19. However, the emergence of SARS-CoV-2 variants that escape from …
due to COVID-19. However, the emergence of SARS-CoV-2 variants that escape from …
BA. 2 and BA. 5 omicron differ immunologically from both BA. 1 omicron and pre-omicron variants
Several studies have shown that SARS-CoV-2 BA. 1 omicron is an immune escape variant.
Meanwhile, however, omicron BA. 2 and BA. 5 became dominant in many countries and …
Meanwhile, however, omicron BA. 2 and BA. 5 became dominant in many countries and …
SARS-CoV-2 correlates of protection from infection against variants of concern
Serum neutralizing antibodies (nAbs) induced by vaccination have been linked to protection
against symptomatic and severe coronavirus disease 2019. However, much less is known …
against symptomatic and severe coronavirus disease 2019. However, much less is known …