Overcoming Barriers to Discovery and Implementation of Equitable Pharmacogenomic Testing in Oncology
SP Shriver, D Adams, BA McKelvey… - Journal of Clinical …, 2024 - ascopubs.org
Pharmacogenomics (PGx), the study of inherited genomic variation and drug response or
safety, is a vital tool in precision medicine. In oncology, testing to identify PGx variants offers …
safety, is a vital tool in precision medicine. In oncology, testing to identify PGx variants offers …
[HTML][HTML] Successful pregnancies in post-kidney transplant couples: four case reports
H Huang, X Liu, X Lin, X Wu, Y Qiu… - Frontiers in …, 2023 - frontiersin.org
Background The fertility of female kidney transplant recipients is increasing with the
progression of transplant management. This article aims to evaluate the clinical prognosis of …
progression of transplant management. This article aims to evaluate the clinical prognosis of …
Omics Sciences in Drug Discovery, Safety, and Pharmacokinetics
Omics sciences study the whole complex of a specific type of biological molecules within an
organism, be it DNA (genomics), RNA (transcriptomics) to the entire class of proteins …
organism, be it DNA (genomics), RNA (transcriptomics) to the entire class of proteins …
TPMT gene polymorphisms (c.238G>C, c.460G>A and c.719A>G) in a healthy Venezuelan population
Background: The presence of polymorphisms in the TPMT gene is associated with adverse
effects in patients treated with standard doses of thiopurine drugs. Scientific evidence …
effects in patients treated with standard doses of thiopurine drugs. Scientific evidence …
Pharmacogenomics of Cancer Chemotherapy: Transporter Polymorphisms and Drug Response
Y Dönmez Çakıl, ZG Özünal, ÖD İşeri, E Yurtcu - 2024 - Springer
Recent advancements in genomic sciences and precision medicine have led to improved
regulatory guidance for pharmacogenomics, particularly in the field of cancer therapies …
regulatory guidance for pharmacogenomics, particularly in the field of cancer therapies …
Implementation and Evaluation Strategies for Pharmacogenetic Testing in Hospital Settings: A Scoping Review
A Wu, EJ Raack, CJD Ross… - Therapeutic Drug …, 2022 - journals.lww.com
Background: Pharmacogenetic testing in clinical settings has improved the safety and
efficacy of drug treatment. There is a growing number of studies evaluating …
efficacy of drug treatment. There is a growing number of studies evaluating …
[HTML][HTML] Ulcerative colitis: an update on management
R Pearce - Medicine Today, 2023 - medicinetoday.com.au
With the continuing evolution of treatments and therapeutic targets for ulcerative colitis (UC),
the outlook for patients with this condition has improved greatly in recent years. GPs are a …
the outlook for patients with this condition has improved greatly in recent years. GPs are a …
The development, implementation, and evaluation of a DPYD testing program in British Columbia
A Wu - 2023 - open.library.ubc.ca
A third of patients develop severe or life-threatening toxicities from fluoropyrimidines, a
commonly prescribed chemotherapeutic. Fluoropyrimidine toxicity is often due to variation in …
commonly prescribed chemotherapeutic. Fluoropyrimidine toxicity is often due to variation in …