Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors

ID Neumann, R Landgraf - Trends in neurosciences, 2012 - cell.com
Oxytocin and vasopressin are regulators of anxiety, stress-coping, and sociality. They are
released within hypothalamic and limbic areas from dendrites, axons, and perikarya …

Environmental influence in the brain, human welfare and mental health

H Tost, FA Champagne, A Meyer-Lindenberg - Nature neuroscience, 2015 - nature.com
The developing human brain is shaped by environmental exposures—for better or worse.
Many exposures relevant to mental health are genuinely social in nature or believed to have …

Genetics of structural and functional brain changes in autism spectrum disorder

S Hashem, S Nisar, AA Bhat, SK Yadav… - Translational …, 2020 - nature.com
Autism spectrum disorder (ASD) is a neurological and developmental disorder characterized
by social impairment and restricted interactive and communicative behaviors. It may occur …

Neural mechanisms of social risk for psychiatric disorders

A Meyer-Lindenberg, H Tost - Nature neuroscience, 2012 - nature.com
Mental health and social life are intimately inter-related, as demonstrated by the frequent
social deficits of psychiatric patients and the increased rate of psychiatric disorders in people …

Oxytocin, stress and social behavior: neurogenetics of the human oxytocin system

R Kumsta, M Heinrichs - Current opinion in neurobiology, 2013 - Elsevier
The neuropeptide oxytocin has had key roles throughout mammalian evolution in the
regulation of complex social cognition and behaviors, such as attachment, parental care …

Oxytocin and vasopressin neural networks: Implications for social behavioral diversity and translational neuroscience

ZV Johnson, LJ Young - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Oxytocin-and vasopressin-related systems are present in invertebrate and vertebrate
bilaterian animals, including humans, and exhibit conserved neuroanatomical and …

Variation in the oxytocin receptor gene predicts brain region–specific expression and social attachment

LB King, H Walum, K Inoue, NW Eyrich, LJ Young - Biological psychiatry, 2016 - Elsevier
Background Oxytocin (OXT) modulates several aspects of social behavior. Intranasal OXT is
a leading candidate for treating social deficits in patients with autism spectrum disorder, and …

Oxytocin improves behavioural and neural deficits in inferring others' social emotions in autism

Y Aoki, N Yahata, T Watanabe, Y Takano, Y Kawakubo… - Brain, 2014 - academic.oup.com
Recent studies have suggested oxytocin's therapeutic effects on deficits in social
communication and interaction in autism spectrum disorder through improvement of emotion …

[HTML][HTML] A spatiotemporal profile of in vivo cerebral blood flow changes following intranasal oxytocin in humans

Y Paloyelis, OM Doyle, FO Zelaya, S Maltezos… - Biological …, 2016 - Elsevier
Background Animal and human studies highlight the role of oxytocin in social cognition and
behavior and the potential of intranasal oxytocin (IN-OT) to treat social impairment in …

Mitigation of sociocommunicational deficits of autism through oxytocin-induced recovery of medial prefrontal activity: a randomized trial

T Watanabe, O Abe, H Kuwabara, N Yahata… - JAMA …, 2014 - jamanetwork.com
Importance Sociocommunicational deficits make it difficult for individuals with autism
spectrum disorders (ASD) to understand communication content with conflicting verbal and …