In the early years of the molecular biology revolution, cancer research was mainly focused
on genetic changes (ie, those that altered DNA sequences). Although this has been …

MicroRNAs (miRNAs) are small non-coding RNAs 18-25 nucleotides in length that
downregulate gene expression during various crucial cell processes such as apoptosis …

MicroRNA (miRNA) opens up a new field for molecular diagnosis of cancer. However, the
role of circulating miRNAs in plasma/serum in cancer diagnosis is not clear. The aim of this …

Colorectal cancer (CRC) develops through a multistage process that results from the
progressive accumulation of genetic mutations, and frequently as a result of mutations in the …

Micro RNAs (miRNAs) are a class of small, non-coding RNA species that play critical roles
throughout cellular development and regulation. miRNA expression patterns taken from …

Background and aims Distant metastasis is a major cause of deaths in patients with
colorectal cancer (CRC), which is partly due to lack of robust metastasis-predictive …

MicroRNAs are a group of small non-coding RNAs that modulate gene expression. The de-
regulation of microRNA expression has been found in several types of cancer. To study the …

Aberrant microRNA (miRNA) expression might be of potential use as diagnostic and
prognostic biomarker for cancers. We reviewed studies published until March 2011 which …

Embryonic genetic programs are reactivated in response to various types of tissue damage,
providing cell plasticity for tissue regeneration or disease progression. In acute conditions …

Abstract E2F transcription factor 1 (E2F1) is a member of the E2F family of transcription
factors. E2F1 binds to DNA with dimerization partner (DP) proteins through an E2 …