Strategies for improving antimicrobial peptide production
Antimicrobial peptides (AMPs) found in a wide range of animal, insect, and plant species are
host defense peptides forming an integral part of their innate immunity. Although the exact …
host defense peptides forming an integral part of their innate immunity. Although the exact …
Reliable protein production in a Pseudomonas fluorescens expression system
DM Retallack, H Jin, L Chew - Protein expression and purification, 2012 - Elsevier
A bottleneck to product development can be reliable expression of active target protein. A
wide array of recombinant proteins in development, including an ever growing number of …
wide array of recombinant proteins in development, including an ever growing number of …
Extension of human GCSF serum half-life by the fusion of albumin binding domain
FY Nikravesh, S Shirkhani, E Bayat, Y Talebkhan… - Scientific Reports, 2022 - nature.com
Granulocyte colony stimulating factor (GCSF) can decrease mortality of patients undergo
chemotherapy through increasing neutrophil counts. Many strategies have been developed …
chemotherapy through increasing neutrophil counts. Many strategies have been developed …
Synthetic pro‐peptide design to enhance the secretion of heterologous proteins by Saccharomyces cerevisiae
JS Cho, HJ Oh, YE Jang, HJ Kim, A Kim… - …, 2022 - Wiley Online Library
Heterologous protein production in Saccharomyces cerevisiae is a useful and effective
strategy with many advantages, including the secretion of proteins that require …
strategy with many advantages, including the secretion of proteins that require …
A topological refactoring design strategy yields highly stable granulopoietic proteins
J Skokowa, B Hernandez Alvarez, M Coles… - Nature …, 2022 - nature.com
Protein therapeutics frequently face major challenges, including complicated production,
instability, poor solubility, and aggregation. De novo protein design can readily address …
instability, poor solubility, and aggregation. De novo protein design can readily address …
Evaluation of a new wide pore core–shell material (Aeris™ WIDEPORE) and comparison with other existing stationary phases for the analysis of intact proteins
S Fekete, R Berky, J Fekete, JL Veuthey… - … of Chromatography A, 2012 - Elsevier
The separation of large biomolecules such as proteins or monoclonal antibodies (mAbs) by
RPLC can be drastically enhanced thanks to the use of columns packed with wide-pore …
RPLC can be drastically enhanced thanks to the use of columns packed with wide-pore …
Safety and Biodistribution Profile of Poly (styrenyl acetal trehalose) and Its Granulocyte Colony Stimulating Factor Conjugate
Poly (styrenyl acetal trehalose)(pSAT), composed of trehalose side chains linked to a
polystyrene backbone via acetals, stabilizes a variety of proteins and enzymes against …
polystyrene backbone via acetals, stabilizes a variety of proteins and enzymes against …
Current status, and the developments of hosts and expression systems for the production of recombinant human cytokines
Cytokines consist of peptides, proteins and glycoproteins, which are biological signaling
molecules, and boost cell-cell communication in immune reactions to stimulate cellular …
molecules, and boost cell-cell communication in immune reactions to stimulate cellular …
[HTML][HTML] Efficient process development of recombinant human granulocyte colony-stimulating factor (rh-GCSF) production in Escherichia coli
V Babaeipour, S Khanchezar, MR Mofid… - Iranian biomedical …, 2015 - ncbi.nlm.nih.gov
Background: The protein hormone granulocyte colony-stimulating factor (GCSF) stimulates
the production of white blood cells and plays an important role in medical treatment of …
the production of white blood cells and plays an important role in medical treatment of …
Soluble prokaryotic overexpression and purification of bioactive human granulocyte colony-stimulating factor by maltose binding protein and protein disulfide …
Human granulocyte colony-stimulating factor (hGCSF), a neutrophil-promoting cytokine, is
an effective therapeutic agent for neutropenia patients who have undergone several cancer …
an effective therapeutic agent for neutropenia patients who have undergone several cancer …