Aim The aim of this systematic review was to critically analyse the available evidence on the
effect of different modalities of alveolar ridge preservation (ARP) as compared to tooth …

Background Mucosal healing is an important therapeutic endpoint in the management of
Crohn's disease (CD) and ulcerative colitis (UC). Limited data exist regarding the …

Background Blood pressure lowering is an established strategy for preventing microvascular
and macrovascular complications of diabetes, but its role in the prevention of diabetes itself …

Purpose To determine the effectiveness of different interventions to slow down the
progression of myopia in children. Methods We searched MEDLINE, EMBASE, Cochrane …

Pooling of direct and indirect evidence from randomized trials, known as mixed treatment
comparisons (MTC), is becoming increasingly common in the clinical literature. MTC allows …

Evidence-based health-care decision making requires comparisons of all relevant
competing interventions. In the absence of randomized, controlled trials involving a direct …

Background Conventional meta-analyses have shown inconsistent results for efficacy of
pharmacological treatments for acute mania. We did a multiple-treatments meta-analysis …

Background Conventional meta-analyses have shown inconsistent results for efficacy of
second-generation antidepressants. We therefore did a multiple-treatments meta-analysis …

This paper sets out a generalised linear model (GLM) framework for the synthesis of data
from randomised controlled trials (RCTs). We describe a common model taking the form of a …

Context There have been substantial changes in the management of men with metastatic
hormone-sensitive prostate cancer (mHSPC) over the past 5 yr, with upfront combination …