ATP and its ultimate degradation product adenosine are potent extracellular signalling
molecules that elicit a variety of pathophysiological functions in the kidney through the …

Individual tissues have significantly different resistance to ischemia–reperfusion damage.
There is still no adequate treatment for the consequences of ischemia–reperfusion damage …

Background and aims Renal ischemia-reperfusion occurs in some clinical conditions such
as kidney surgery that can leads to acute renal failure. The aim of this study was to …

Intestinal ischemia‐reperfusion (I/R) may induce cell/tissue injuries, leading to multiple
organ failure. Based on our preexperiments, we proposed that sesamin could protect …

Aims Berberine is endowed with anti-oxidant, anti-inflammatory and anti-fibrotic effects. This
study explored the role of adenosine A 2a receptor (A 2a R) activation and SDF-1/CXCR4 …

Context: Acute kidney injury (AKI) is considered a major public health concern in today's
world. Sepsis‐induced AKI is large as a result of exposure to lipopolysaccharide (LPS) that …

Various studies have evidenced the neuroprotective role of PDE4 inhibitors. However,
whether PDE4 inhibitor, Piclamilast pharmacological post-treatment is protective during …

Acute kidney injury (AKI) is a complex condition which has an intricate pathology mostly
involving hemodynamic, inflammatory, and direct toxic effects at the cellular level with high …

Ethnopharmacological relevance Crateva nurvala stem bark is commonly used in Ayruveda
in treatment of many renal injuries, eg, urinary lithiasis, diuretic and nephroprotective …

Purpose The present study investigated the nephron-testicular protective effects of sesamin
against cisplatin (CP)-induced acute renal and testicular injuries. Methods Thirty-two male …