Human cytochromes P450 in health and disease
There are 18 mammalian cytochrome P450 (CYP) families, which encode 57 genes in the
human genome. CYP2, CYP3 and CYP4 families contain far more genes than the other 15 …
human genome. CYP2, CYP3 and CYP4 families contain far more genes than the other 15 …
[HTML][HTML] Membrane-attached mammalian cytochromes P450: An overview of the membrane's effects on structure, drug binding, and interactions with redox partners
Mammalian cytochromes P450 are an important class of enzymes involved in the
biotransformation of many endo-and exogenous compounds. Cytochrome P450 isoforms …
biotransformation of many endo-and exogenous compounds. Cytochrome P450 isoforms …
[图书][B] Handbook of vitamins
J Zempleni, JW Suttie, JF Gregory III, PJ Stover - 2013 - books.google.com
Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …
edition of a bestseller presents comprehensive summaries that analyze the chemical …
NADPH P450 oxidoreductase: structure, function, and pathology of diseases
Cytochrome P450 oxidoreductase (POR) is an enzyme that is essential for multiple
metabolic processes, chiefly among them are reactions catalyzed by cytochrome P450 …
metabolic processes, chiefly among them are reactions catalyzed by cytochrome P450 …
NADPH–cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology
DS Riddick, X Ding, CR Wolf, TD Porter… - Drug Metabolism and …, 2013 - ASPET
This is a report on a symposium sponsored by the American Society for Pharmacology and
Experimental Therapeutics and held at the Experimental Biology 2012 meeting in San …
Experimental Therapeutics and held at the Experimental Biology 2012 meeting in San …
Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
SB Jensen, S Thodberg, S Parween, ME Moses… - Nature …, 2021 - nature.com
Metabolic control is mediated by the dynamic assemblies and function of multiple redox
enzymes. A key element in these assemblies, the P450 oxidoreductase (POR), donates …
enzymes. A key element in these assemblies, the P450 oxidoreductase (POR), donates …
NADPH–cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family
NADPH–cytochrome P450 oxidoreductase (CYPOR) and nitric oxide synthase (NOS), two
members of the diflavin oxidoreductase family, are multi-domain enzymes containing distinct …
members of the diflavin oxidoreductase family, are multi-domain enzymes containing distinct …
Plasticity of specialized metabolism as mediated by dynamic metabolons
The formation of specialized metabolites enables plants to respond to biotic and abiotic
stresses, but requires the sequential action of multiple enzymes. To facilitate swift production …
stresses, but requires the sequential action of multiple enzymes. To facilitate swift production …
Unusual properties of the cytochrome P450 superfamily
DC Lamb, MR Waterman - Philosophical Transactions of …, 2013 - royalsocietypublishing.org
During the early years of cytochrome P450 research, a picture of conserved properties arose
from studies of mammalian forms of these monooxygenases. They included the protohaem …
from studies of mammalian forms of these monooxygenases. They included the protohaem …
P450 Oxidoreductase deficiency: analysis of mutations and polymorphisms
Cytochrome P450 oxidoreductase (POR) is required for metabolic reactions of steroid and
drug metabolizing cytochrome P450 proteins located in endoplasmic reticulum. Mutations in …
drug metabolizing cytochrome P450 proteins located in endoplasmic reticulum. Mutations in …