Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches

W Wang, Z Huang, Y Huang, X Zhang, J Huang… - Advanced Drug Delivery …, 2022 - Elsevier
Pulmonary delivery of nanomedicines is very promising in lung local disease treatments
whereas several physiological barriers limit its application via the interaction with inhaled …

Recent advances in nanoparticle applications in respiratory disorders: a review

ME Taghavizadeh Yazdi, M Qayoomian… - Frontiers in …, 2023 - frontiersin.org
Various nanoparticles are used in the discovery of new nanomedicine to overcome the
shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to …

Application of PLGA as a biodegradable and biocompatible polymer for pulmonary delivery of drugs

R Mahar, A Chakraborty, N Nainwal, R Bahuguna… - Aaps Pharmscitech, 2023 - Springer
Pulmonary administration of biodegradable polymeric formulation is beneficial in the
treatment of various respiratory diseases. For respiratory delivery, the polymer must be non …

Inhaled nano-based therapeutics for pulmonary fibrosis: recent advances and future prospects

Q Wan, X Zhang, D Zhou, R Xie, Y Cai, K Zhang… - Journal of …, 2023 - Springer
It is reported that pulmonary fibrosis has become one of the major long-term complications of
COVID-19, even in asymptomatic individuals. Currently, despite the best efforts of the global …

mRNA nanodelivery systems: targeting strategies and administration routes

M Yuan, Z Han, Y Liang, Y Sun, B He… - Biomaterials …, 2023 - spj.science.org
With the great success of coronavirus disease (COVID-19) messenger ribonucleic acid
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …

Inhalable CAR-T cell-derived exosomes as paclitaxel carriers for treating lung cancer

W Zheng, T Zhu, L Tang, Z Li, G Jiang… - Journal of Translational …, 2023 - Springer
Background Non-small cell lung cancer (NSCLC) is a worldwide health threat with high
annual morbidity and mortality. Chemotherapeutic drugs such as paclitaxel (PTX) have been …

Recent advances in targeted cancer therapy: Are PDCs the next generation of ADCs?

B Zhang, M Wang, L Sun, J Liu, L Yin… - Journal of Medicinal …, 2024 - ACS Publications
Antibody–drug conjugates (ADCs) comprise antibodies, cytotoxic payloads, and linkers,
which can integrate the advantages of antibodies and small molecule drugs to achieve …

Dry powder inhalers of antitubercular drugs

N Nainwal, Y Sharma, V Jakhmola - Tuberculosis, 2022 - Elsevier
Despite advancements in the medical and pharmaceutical fields, tuberculosis remains a
major health problem globally. Patients do not widely accept the conventional approach to …

Lipid-based nanotechnology: Liposome

Y Jiang, W Li, Z Wang, J Lu - Pharmaceutics, 2023 - mdpi.com
Over the past several decades, liposomes have been extensively developed and used for
various clinical applications such as in pharmaceutical, cosmetic, and dietetic fields, due to …

[HTML][HTML] Engineering of pulmonary surfactant corona on inhaled nanoparticles to operate in the lung system

M Falahati, A Hasan, HA Zeinabad, V Serpooshan… - Nano Today, 2023 - Elsevier
Exposure of inhaled nanoparticles (NPs) to the deep lung tissue results in the adsorption of
pulmonary surfactant (PSf) on the surface of NPs and the formation of a biomolecular …